A study of fatty acids in fecal fat in various malabsorption syndromes.

スポンサーリンク

概要

• 論文の詳細を見る

• Qualitative and quantitative analysis of fatty acids in fecal fat was performed in healthy controls and five disease groups: subtotal gastrectomy (Billroth I), subtotal gastrectomy (Billroth II), total gastrectomy, Crohn's disease and ileal resection. The composition of eight different fatty acids including 10-hydroxystearic acid (10-OHSA), which is produced predominantly from dietary oleic acid by intestinal bacteria, was measured with high-performance liquid chromatography (HPLC).All five disease groups had significantly higher fecal fat excretion than the control population. Fecal fatty acids concentration was increased in Billroth II and total gastrectomy. The percentage of 10-OHSA in fecal fatty acids was increased significantly in Billroth I, Billroth II, total gastrectomy and Crohn's disease. The ratio of 10-OHSA to oleic acid in fecal fat, which may represent the degree of bacterial conversion of oleic acid to 10-OHSA, was increased significantly in all disease groups. There was a linear relationship between the percentage of 10-OHSA and fecal fat excretion. These findings suggest there is a close relationship between bacterial overgrowth and fat malabsorption.

• 財団法人 日本消化器病学会の論文

著者

• 斉藤 治

  大阪医科大学第2内科

• 斉藤 治

  大阪医科大学第2内科学教室

関連論文

• 炎症性腸疾患 (IBD) における末梢血NK活性とNK subsets の検討
• blind loop 部小腸に多発性潰瘍を認め, 蛋白漏出性腸症を呈した1例
• A study of lymphocyte subset distribution and HLA-DR antigen expression in peripheral blood and in mucosa of the stomach, small intestine and colon.
• A case of ischemic lesion in the large intestine associated with Buerger's disease.
• Abnormal bile acid metabolism in patients with ileal disease and ileal resection-effect of oral ursodeoxycholic acid administration.
• A study of fatty acids in fecal fat in various malabsorption syndromes.

スポンサーリンク