Effects on the heart and lung after endoscopic injection sclerotherapy for esophageal varices.

概要

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The changes of cardiopulmonary function after endoscopic injection sclerotherapy for esophageal varices were studied. Endoscopic injection sclerotherapy was performed by intravariceal injection of 5% ethanolamine oleate. Immediately after injection, pulmonary arterial resistance and pulmonary arterial pressure increased (p<0.01). At the same time, arterial oxygen pressure decreased (p<0.01), and physiological pulmonary shunt ratio and alveolar-arterial oxygen tension difference increased (p<0.01). They recovered within 3 days after injection. These changes suggest the presence of a transient pulmonary diffusion disorder. They were not observed after esophagoscopy without injection of the sclerosing agent. Therefore, these results were considered to be due to injection of the sclerosing agent.