:(2) Relationship Between Hepatic Lipid Content and Various Blood Hormone Levels Including Insulin

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概要

• 論文の詳細を見る

• A relationship between hepatic lipid content and various blood hormone levels including insulin (IRI) was studied in 23 obese subjects showing more than 15% over ideal body weight without diabetes mellitus and alcohol abuse (14 men, 9 women).The hepatic lipid content in obese patients did not correlate with fasting blood glucose levels and the sum of glucose values during 50g OGTT (∑BS), but positively with basal levels of serum IRI, the sum of IRI values during OGTT (∑IRI), ΔMRI/ΔBS at 30 min, ∑IRI/∑BS and fasting FFA levels. Thus it is suggested that hyperinsulinemia due to a diminished insulin sensitivity of the peripheral tissues is of importance for hepatic fatty change in the obese subjects.The hepatic lipid content was not influenced by basal levels of cortisol, thyroxine and growth hormone.

• 財団法人 日本消化器病学会の論文

著者

• 菅谷 仁

  独協医科大学第二内科

• 前原 操

  独協医科大学第二内科

• 原田 尚

  独協医科大学第二内科

• 吉次 通泰

  独協医科大学第2内科

• 原田 尚

  独協医科大学第2内科

• 菅谷 仁

  独協医科大学第2内科

• 前原 操

  独協医科大学第2内科

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