UNEVEN SECRETORY RESPONSE OF CANINE PANCREAS TO EXOGENOUS SECRETIN
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概要
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The pancreatic response to exogenous secretin was studied in 24 anesthetized dogs provided with two pancreatic fistulas. The pancreatic secretions from the right and left lobes were collected separately and simultaneously, through polyethylene tubes inserted into the main duct at the orifice of the duodenum and at the pancreatic angle.Secretin-stimulated volume and electrolyte outputs, when calculated per wet weight of the tissue, were significantly greater in the left lobe than in the right lobe. There were no significant difference in electrolyte concentrations and amylase secretion.The reason of the dominant secretory response in the left lobe, at present, is not clear. It may be largely due to the difference of the absolute amount of secretin delivered to its target cells, resulting from the difference of blood flow rate.
- 財団法人 日本消化器病学会の論文
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