Different effects of polaprezinc and zinc chloride on zinc supplementation in elderly bedridden patients receiving enteral nutrition
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概要
- 論文の詳細を見る
Aims : The purposes of this study were to compare the efTects of polaprezinc and zinc chloride on serumzinc and copper concentrations in elderly bedridden patients receiving enteral nutrition, and to examinethe efTects of polaprezinc on pressure ulcer healing in those patients. Methods : Seven elderly bedriddenpatients receiving enteral nutrition entered into a crossover study of 2-week treatment periods withpolaprezinc or zinc chloride, separated by a 4week washout period. Serum zinc and copper concentra-tions were compared between both treatment periods. Then, another five elderly patients with pressureulcers were treated with polaprezinc for 8 weeks. The assessment of pressure ulcers was made weeklyusing the PUSH tool 3.0. Results: After 2 weeks, polaprezinc significantly increased serum zincconcentrations, decreased serum copper/zinc ratios, but did not change serum copper concentrations.Zinc chloride did not change these three parameters. Polaprezinc also produced a significant improve-ment in PUSH score and a reduction of 81 96 in ulcer area after 8 weeks. Conclusion: The efficiencyof absorption of zinc from polaprezinc may be much higher than that from zinc chloride in elderlybedridden patients receiving enteral nutrition. Polaprezinc may also have a beneficial efTect on pressureulcer healing in those patients.
- 北関東医学会の論文
著者
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Koyama Hiroshi
Department of Cardiology, Fukuoka Tokushukai Medical center
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Ohyama Yoshio
Department of General Medicine, Gunma University Graduate School of Medicine
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Ohyama Yoshio
Department Of General Medicine Graduate School Of Medicine Gunma University
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Tamura Junichi
Department Of General Medicine Gunma University School Of Medicine
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Kawada Etsuo
Department Of General Medicine Graduate School Of Medicine Gunma University
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Morita Toyoho
Department Of Medicine Ninosawa Hospital
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Oidov Batgerel
Department Of General Medicine Graduate School Of Medicine Gunma University
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Sakamoto Hironosuke
Medical Education Center, Gunma University Graduate School of Medicine
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Sato Hiroko
Department Of General Medicine Gunma University Hospital
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Oidov Batgerel
Department of General Medicine, Gunma University Graduate School of Medicine
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Ohyama Yoshio
Department of Emergency Medicine, Gunma University Graduate School of Medicine
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Kawada Etsuo
Department of Internal Medicine, Ninosawa Hospital
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Tamura Jun'ichi
Department of General Medicine, Gunma University Graduate School of Medicine
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KOYAMA Hiroshi
Department of Public Health, Gunma University Graduate School of Medicine
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Morita Toyoho
Department of Geriatrics, Ninosawa Hospital
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