Restoration of Abnormally High CD4/CD8 Ratio and Low Natural Killer Cell Activity by Vitamin B12 Therapy in a Patient with Post-gastrectomy Megaloblastic Anemia.
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概要
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A patient with post-gastrectomy megaloblastic anemia is described. Initially, the CD4/CD8 ratio of blood cells was abnormally high and the level of natural killer cell activity was markedly low. These abnormalities were, however, restored by vitamin B12 treatment. Taken together with our prior report on a patient with pernicious anemia in whom the decreased level of CD8-positive blood cells was corrected by vitamin B12 therapy, it may be considered that the reversible CD4/CD8 imbalance of blood cells noted in some cases of pernicious anemia is not pathognomonic for the disease but secondary to vitamin B12 deficiency.(Internal Medicine 31 : 125-126, 1992)
- 社団法人 日本内科学会の論文
著者
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Okamoto Kiyoshi
Department Of Anatomy Fukuoka University School Of Medicine
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Kawada Etsuo
Department Of General Medicine Graduate School Of Medicine Gunma University
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Kubota Kazuo
Department Of Medicine And Division Of Rehabilitation Kusatsu Branch Hospital Gunma University Schoo
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KAWADA Etsuo
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine
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KURABAYASHI Hitoshi
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine
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SHIRAKURA Takuo
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine
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OKAMOTO Kiyoshi
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine
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KUBOTA Kazuo
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine
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