95Zr-95Nbの生体におよぼす影響に関する実験的研究(2) : ラット経口投与時の体内分布と排泄
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As previously reported, 95Zr-95Nb were detected in fallout and also in vegetation in the Fukuoka Prefecture even at other times besides occasions of nuclear explosion. It is suggested that an intake of a considerable dose of these radioactive agents may occur in common daily dietary food. In succession of Report I, which described the distribution and excretion of these radioactive agents in subcutaneously injected rats, an oral administration in rats using intubation technique was carried out consecutively and the distribution and excretion of these radioactive agents were pursued by using a G. M.-tube counter.1) Radioactivities of every observed organ other than the stomach revealed the maximum value at the 24th hour after the administration, rapidly reduced up to the 7th day and very slowly decreasing.2) A remarkable deposition of 95Zr-95Nb in tibia as distinguished from other organs was not observed in early stages after the oral administration although it differed from the former subcutaneous injection. But on the 63th day after administration, an amount of deposition of 95Zr-95Nb in second place after the spleen, was detected in the tibia.3) The amount of 66.22% of the total excretion of 95Zr-95Nb was excreted by the 7th day after administration and also was measured in feces more than in urine. From the fact mentioned above, it is considered that 95Zr-95Nb given by oral administration to rats may have poor absorption by the alimentary tract.
- 日本衛生学会の論文
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