BIOCHEMICAL STUDIES ON HUMAN SALIVARY PROTEINS II. PRELIMINARY CHARACTERIZATION OF A FRACTION WITH HYPOCALCEMIC AND LEUKOCYTOSIS-PROMOTING ACTIVITIES IN THE DIGEST OF SALIVA-PAROTIN-A BY PRONASE P
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概要
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Fractionation of the digest of saliva-parotin-A by Pronase P was carried out by gel filtration on Sephadex G-25 column to give five fractions (P-1--V), using 1<I>M</I> acetic acid as eluant. Of five fractions, only P-I containing peptides of fairly large molecular weights showed potent hypocalcemic and leukocytosis-promoting activities in rabbits. Electrophoretical behavior and amino acid pattern of P-I were quite different from those of saliva-parotin-A.
- 社団法人 日本内分泌学会の論文
著者
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Ueki Hiroshi
Department Of Biochemistry Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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KUBOTA YUKIHO
Department of Physiological Chemistry Faculty of Pharmaceutical Sciences, University of Tokyo
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ITO YOSOJI
Department of Physiological Chemistry Faculty of Pharmaceutical Sciences, University of Tokyo
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KUBOTA YUKIHO
Department of Biochemistry, Faculty of Pharmaceutical Sciences, Kumamoto University
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UEKI HIROSHI
Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
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