Initiation of Milk Secretion in the Male Rat by Single Injections of Reserpine
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概要
- 論文の詳細を見る
Mammary gland development and secretion in male rats were induced by single injections of reserpine. The lactogenic effect of reserpine was most marked when a dose of 1mg/kg was given. The alveoli and ducts of the male mammary glands were greatly distended with milky secretion. Similar changes in the glands were also observed but in a smaller number of animals when a dose of 0.5-0.75mg/kg was given. Nialamide (250mg/kg) counteracted the effect of reserpine (1mg/kg) when given 16-18 hours before the reserpine injection. A similar inhibition was obtained by L-DOPA (250mg/kg) when injected one hour after the reserpine injection. These results provide the evidence that the male pituitary is capable of secreting prolactin in response to reserpine, and also suggest the involvement of monoaminergic mechanisms in the process of prolactin release in the male rat.
- 社団法人 日本内分泌学会の論文
著者
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MASUDA SAKAE
Department of Surgery, Nippon Medical School Second Hospital
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Arai Yasumasa
Department Of Anatomy Juntendo University School Of Medicine
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Suzuki Yoshihide
Department Of Anatomy Juntendo University School Of Medicine
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KUBOKURA AKIO
Juntendo University School of Medicine
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Arai Yasumasa
Department Of Anatomy Jaunted University Scool Of Medicine
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SUZUKI YOSHIHIDE
Departments of Anatomy and Neuropsychiatry
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MASUDA SAKAE
Department of Anatomy, Juntendo University School of Medicine
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MASUDA SAKAE
Departments of Anatomy and Neuropsychiatry
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