Calcitonin Inhibition of Gastric Secretion in Rat
スポンサーリンク
概要
- 論文の詳細を見る
The recent discovery of the stimulatory effect of gastrin or pancreozymin on the secretion of calcitonin in the pig has prompted us to study the gastrointestinal effect of calcitonin in rats.<BR>The marked increase in the gastric acid and pepsin accumulation in rats in which the pylorus was ligated for 9hr was significantly inhibited by the prior treatment with 2 MRC U of purified porcine calcitonin.<BR>This inhibitory effect of porcine calcitonin on the gastric acid and pepsin accumulation was dose dependent. Furthermore, the development of acute gastric ulcer in these rats was completely prevented by the s.c. administration of 2 MRC U of porcine calcitonin.
- 社団法人 日本内分泌学会の論文
著者
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Ito Hideki
Department Of Endocrinology Tokyo Metropolitan Geriatric Hospital
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ORIMO HAJIME
Section of Endocrinology, Tokyo yoikin Hospital
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OYAMA TOSHIRO
Section of Endocrinology, Tokyo Metropolitan Geriatric Hospital
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Ito Hideki
Department of Bioresource Science, Faculty of Agriculture, Kagawa University
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ORIMO HAJIME
Section of Endocrinology Tokyo Metropolitan Geriatric Hospital
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ORIMO HAJIME
Section of Endocrinology, Tokyo Metropolitan Geriatric Hospital
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ITO HIDEKI
Department of Geriatrics, Faculty of Medicine, University of Tokyo
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