A Case Report on Disequilibrium Hypercalcemia in Hyperthyroidism : Comparison of Calcium Metabolism with Other Patients with Hyperthyroidism

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概要

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• The patient, a 30-year-old woman, was admitted to Itoh Hospital in February, 1979 for hyperthyroidism. She had a history of pyelonephritis and recurrent urinary tract infection. Laboratory data on admission revealed overt hyperthyroidism (T<SUB>3</SUB>: 405ng/dl, T<SUB>4</SUB>: 22.5μg/dl and T<SUB>3</SUB>U: 57.0%), severe hypercalcemia of 12.6mg/dl and hypercalciuria. The PSP excretion and GFR were both decreased. Serum c-PTH was nondetectable. As the thyroid function improved, there was a gradual decrease and later normalization of plasma calcium, phosphate and urinary calcium excretion. When subtotal thyroidectomy was performed on October 19, 1979, hypertrophy of the parathyroid gland was not demonstrated.<BR>In comparison with 98 other hyperthyroid patients, the pathogenesis of hypercalcemia was discussed.<BR>In conclusion, hypercalcemia in the patient, T. Y., was regarded as a kind of disequilibrium hypercalcemia which resulted from a combination of increased bone turnover and decreased calcium excretion by the kidney.

• 社団法人 日本内分泌学会の論文

著者

• Wada Masahisa

  Second Dept. Of Intern. Med. Osaka City Univ. School Of Med.

• Inaba Masaaki

  Second Division Of Surgery Kanagawa Cancer Center

• Morii Hirotoshi

  Second Department Of Internal Medicine Osaka City University Medical School

• OHNO MARIKO

  Second Department of Internal Medicine Osaka City University

• OKAMOTO TERUO

  Second Department of Internal Medicine, Osaka City University Medical School

• HAMADA NOBORU

  Second Department of Internal Medicine, Osaka City University

• ITOH KUNIHIKO

  Itoh Hospital

• MIMURA TAKASHI

  Itoh Hospital

• YAMAKAWA JUN-ICHI

  Second Department of Internal Medicine, Osaka City University

• IKEDA SACHIYO

  Second Department of Internal Medicine, Osaka City University

• MORII HIROTOSHI

  Second Department of Internal Medicine Osaka City University

• INABA MASAAKI

  Second Department of Internal Medicine, Osaka City University

• OHNO MARIKO

  Second Department of Internal Medicine, Osaka City University

• OKAMOTO TERUO

  Second Department of Internal Medicine, Osaka City University

• WADA MASAHISA

  Second Department of Internal Medicine, Osaka City University

• WADA MASAHISA

  Second Department of Internal Medicine Osaka City University Meaical School

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