ヨウ化サマリウムを用いる迅速還元反応
スポンサーリンク
概要
- 論文の詳細を見る
Recent study in this laboratory is reviewed The single electron donor ability of samarium diiodide (SmI<SUB>2</SUB>) can be enhanced with ligands around of Sm (II) when a sufficient electron is supplied from ligands. Mechanistic consideration of this enhancement led us to find that carboxylic acid, ester, amide, nitrile and the other functionalities were rapidly reduced with SmI<SUB>2</SUB> in the presence of base, acid and water as ligands at room temperature in good yields. Particularly, these systems reduced directly carboxylic acid into alcohol and SmI<SUB>2</SUB>-85% phosphoric acid system reduced aromatic primary amide to aldehyde in good yield Pyridines were similarly reduced to piperidines with SmI<SUB>2</SUB>-base or water system and aromatic nucleus of phenol derivatives was rapidly reduced with SmI<SUB>2</SUB>-base system Furthermore, carboxylic acid, ester, amide and nitrile were rapidly reduced with Sm or Yb metal-hydrochloric acid system.<BR>The striking characteristic of these reduction is mild conditions, short reaction time (within a few secondsminutes), high yield of reductive products and one pot reaction with facile method.
- 社団法人 有機合成化学協会の論文
著者
関連論文
- N-異項還化合物のSm-MeSO_3H系による還元反応
- 新規の選択還元を含むヨウ化サマリウムによる各種官能基の迅速還元反応
- NOVEL AND FACILE REDUCTION OF HETEROCYCLIC COMPOUNDS WITH LANTHANOID METAL-HYDROCHLORIC ACID SYSTEM
- NOVEL REDUCTION OF CARBOXYLIC ACID, ESTER, AMIDE AND NITRILE WITH SAMARIUM OR YTTERIBIUM METAL-HYDROCHLORIC ACID SYSTEM
- ヨウ化サマリウムを用いる迅速還元反応
- SmI_2-塩基系による各種官能基の還元反応
- ヨウ化サマリウムを用いる迅速還元反応
- Studies of Reduction of Various Organic Compounds with the Nickel(II) Chloride-Zinc System
- Studies of Reduction with Dimethoxyborane-Transition Metal Boride Systems
- Selective Reduction of Aromatic Nitro Compounds with Nickel Boride
- Studies of Reduction with Dimethoxyborane-Transition Metal Salt Systems. I. : Reduction of Nitriles, Aldehydes and Ketones with Dimethoxyborane-Transition Metal Salt Systems
- Studies of Reduction with the Sodium Borohydride-Transition Metal Boride System. I. : Reduction of Nitro and the Other Functional Groups with the Sodium Borohydride-Nickel Boride System
- Selective Reduction of Imines with the Diborane-Methanol System
- Reactions of Trialkylborane. VI. : Reduction of Carbonyl Compounds with Trialkylborane
- Studies of Reduction with the Diborane-Transition Metal Salt system
- Reduction of Heterocyclic Compounds. II. Reduction of Heterocyclic Compounds with Sodium Borohydride-Transition Metal Salt Systems
- Reduction with Sodium Borohydride-Transition Metal Salt Systems. I. Reduction of Aromatic Nitro Compounds with the Sodium Borohydride-Nickelous Chloride System
- 複素環化合物の還元反応(第1報)複素環化合物のジボランによる還元反応
- Sodium Borohydrideの反応(第3報)芳香族ニトロ化合物のSodium Borohydrideによる還元反応
- Sodium Borohydrideの反応(第2報) : Carboxylic AcidおよびEsterのSodium Borohydrideによる還元反応
- トリアルキルボランの反応(第5報)トリアルキルボラン存在下における酸アミド化合物の反応
- トリアルキルボランの反応(第4報) トリアルキルボランと芳香族スルホニルクロライドとの反応
- トリアルキルボランの反応(第3報) トリアルキルボランとカルボニル化合物との反応
- 環状酸無水物の水素化硼素ナトリウムによる還元反応
- トリアルキルボランの反応(第2報)トリアルキルボランと芳香族ニトロ化合物との反応
- トリアルキルボランの反応(第1報)トリアルキルボランと芳香族アミンN-オキシドとの反応
- EnamineのHydroborationと還元反応(第3報)Exo-enamineおよびEndo-enamineとDiboraneおよびSodium Borohydrideとの反応
- イミノアセタール類のランタノイドトリフラートを酸触媒とする閉環反応