Studies on Derivatives of Substituted Benzene-sulfonyl Carbamic Acid. III:N-Substituted benzene-sulfonyl-N'-alkyl-carbodiimides.

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Upon treatment with alkali, N-substituted benzenesulfonyl-N'-alkyl-chloroform-amidines were found to give the corresponding carbodiimides in the presence of hydrophobic solvents, such as chloroform and benzene, etc., in a theoretical yield. When N-substituted benzenesulfonyl-N'-alkyl-chloroformamidine was heated above its melting point, hydrogen chloride was liberated and the corresponding carbodii-mide was produced.The above mentioned carbodiimides were again converted back to the original chloroformamidines when treated with hydrogen chloride.N-substituted benzenesulfonyl-N'-alkyl-urea, used as an antihypertentive agent, O-methylisourea, and guanidines were prepared in good yields from the carbodii- mides as obtained above.
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