Specificity in chromosomal abnormalities in mouse bone marrows induced by the difference of the condition of irradiation.
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概要
- 論文の詳細を見る
Twenty-two young adult C3H/He male mice were exposed to 3Gy, preferable condition to induce myeloid leukemias, and another group of 22 males to the fractionated irradiation of 4×1.7Gy, preferable to lymphoid tumors. The stable type aberrations of chromosomes in bone marrow cells of those mice were analyzed within 3 months and in longer than 15 months after final irradiations in both groups. The mice exposed to 3Gy had cells with abnormal chromosome no. 2 more than those exposed to 4×1.7Gy did. The number of cells with chromosomal abnormalities in general increased at the late stage in the mice given 4×1.7Gy, but not in the mice received 3Gy. The chromosomes whose frequencies exceeded mean plus two times the value of standard deviation were the chromosome no. 2 in the former and the chromosome no. 11 in the latter.
- 日本学士院の論文
著者
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Ichikawa Tomohiko
Department Of Material Science And Technology School Of High-technology For Human Welfare Tokai Univ
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Hayata Isamu
National Institute of Radiological Science
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ICHIKAWA Yayoi
National Institute of Radiological Sciences
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