THERAPY AND PREVENTION OF LEAD POISON-ING WITH CALCIUM VERSENATE
スポンサーリンク
概要
- 論文の詳細を見る
Experiments on the effectiveness of Ca EDTA upon lead poisoning were undertaken, on dogs and lead workers.1. In the animal experiments the following conclusion were reached.a. The parenteral administration of Ca EDTA changed the distribution of lead in arterial blood, and plasma lead was increased. This is thought to come from the red corpuscles in which the greatest portion of lead in the blood was found when lead absorption occurs, and also from the extravascular tissues.b. Decrease of A/G ratio was not prevented by the administration of the drug, although the symptoms, including anemia, were kept normal. This indicates that the decrease of A/G ratio appears in the earlier stage of lead poisoning, with the exception of coproporphyrinuria, as has beenn stated previously.2. Clinical and prophylactic use of the drug yielded the following results.a. Intravenous therapy did not increase the lead concentration in the blood but the urinary lead showed its highest level in the urine after three hours administration.b. Higher urinary lead excretion by oral administration was obscrved in only a few patients in contrast with the results seen by intravenous injection. This indicates that the absorption from the intenstine is very low, following the oral administration.c. Oral administration (which was extended over a period of more than six months) for the purpose of preventing chronic, potential lead poisoning, was successful in decreasing both the blood lead and urine lead quantity, in preventing appearance of the symptoms, and in improving anemia.d. Further study is necessary to determine a proper, daily, oral dosage.
- The Keio Journal of Medicineの論文
著者
-
Mori Akira
Departmenet Of Animal Husbandry Faculty Of Agriculture Tohoku University
-
SAKAGUCHI TAKEO
Department of Preventiue Medicine & Public Health, School of Medicine, Keio University
-
HARASHIMA SUSUMU
Department of Preventiue Medicine & Public Health, School of Medicine, Keio University
-
TSUCHIYA KENZABURO
Department of Preventiue Medicine & Public Health, School of Medicine, Keio University
-
KONDO HARUO
Department of Preventiue Medicine & Public Health, School of Medicine, Keio University
-
MOTOUCHI MASAO
Department of Preventiue Medicine & Public Health, School of Medicine, Keio University
関連論文
- A Structural Study of the Carboxyl Terminal Region of the Human Erytheocyte Band 3 Protein
- X-ray Phase-Contrast Imaging and X-ray Absorption Fine Structure Analysis using Parametric X-ray Radiation Generated at LEBRA, Nihon University
- A Novel Suicide Gene Therapy System for p53-Mutated Cells Using a Wild-Type p53-Specific Promoter and Cre/loxP Switch
- Characteristics of recurrent hepatocellular carcinoma in Japan and our surgical experience
- Common carotid artery stiffness with metabolic alteration after menopause(Others 4)
- Estriol versus estradiol in hormone replacement therapy : Consideration on lipid and bone metabolism(Others 3)
- Assessment of vascular elasticity of small for gestational age infants with antenatal umbilical placental insufficiency(Session20 Peninatology5)
- Stiffness of systemic arteries in women with a history of severe preeclampsia is increased and is related to the lipoprotein(a)level.(Session7 Others1)
- Hormone replacement therapy and common carotid artery stiffness with lipid metabolism(Others 4)
- 17-12.Impact of menopause on lipid and bone metabolism and effect of hormone replacement therapy. (Session 18 Others 2)
- Impact of Menopause on Lipid and Bone Metabolism and Effect of Hormone Replacement Therapy
- Hepatocellular carcinoma development induced by conditional β-catenin activation in Lkb1^ mice
- Field Observation of Maternal Attendance of Eggs in a Madagascan Snake, Leioheterodon madagascariensis
- Infected Abdominal Aortic Aneurysm Caused by Campylobacter fetus Subspecies fetus:Report of a Case
- Factors Affecting the Intra-populational Variation in Dorsal Color Pattern of an Iguanian Lizard, Oplurus cuvieri cuvieri
- BIOLOGICAL EFFECTS OF EXPOSURE TO LEAD IN AMBIENT AIR AMONG TOKYO INHABITANTS
- EPIDEMIOLOGICAL SIGNIFICANCE OF HISTOPATHOLOGICAL LUNG CANCER TYPES
- STUDIES ON THE REPRODUCTIVE FAILURE OF RAM CAUSED BY UNDERFEEDING IV. ON THE TESTICULAR FUNCTION AND THE POTENCY OF ANTERIOR PITUITARY IN UNDERFED RAM
- Omental Delivery of Prostaglandin E_1 Effectively Increases Portal Venous Blood Flow in 66% - Hepatectomized Rats
- Enhancement of Portal Blood Flow by Ursodesoxycholic Acid in Partially Hepatectomized Rats
- Fat Liquefaction of Adipose Tissue Using Atmospheric-Pressure Plasma Irradiation
- Results of surgical treatment for recurrent hepatocellular carcinoma ; comparison of outcome among patients with multicentric carcinogenesis, intrahepatic metastasis, and extrahepatic recurrence
- Feeding Characteristics of a Japanese Pitviper, Ovophis okinavensis, on Okinawa Island: Seasonally Biased but Ontogenetically Stable Exploitation on Small Frogs
- Penetration by a Huge Abdominal Aortic Aneurysm into the Lumbar Vertebrae: Report of a Case
- Intermittent Claudication Associated with Persistent Sciatic Artery:Report of Two Cases
- Quantitative Evaluation of Individual Snake Coloration by Use of Principal Components Analysis with Variable Selection
- Early Growth of Elaphe quadrivirgata from an Insular Gigantic Population
- Literature Survey on Predators of Snakes in Japan
- STUDIES ON THE PROJECTION OF URINE : SECOND REPORT : UROFLOMETER (UROFLOGRAM) AND MICTURITION VELOCITY
- Thermolysis of Spiro [2,2-dimethylbicyclo [2.2.2] octa-5,7-diene-3,3-cyclopropene]. An Attempt to Synthesize 4,4-Dimethylmethylenecyclopropene
- THE EFFECT OF ANTIBIOTICS ON FERTILIZED OVA
- STUDIES ON THE PROJECTION OF URINE : FOURTH REPORT : CURVES OF THE PROGRESS OF INTRAVESICAL PRESSURE DURING MICTURITION
- STUDIES ON THE PROJECTION OF URINE : THIRD REPORT : PROJECTION CURVE
- STUDIES ON THE REPRODUCTIVE FAILURE OF RAM CAUSED BY UNDERFEEDING II. ON THE EFFECTS OF FEEDING MILK, PORK AND EGGS TO IMPOTENT RAM
- EFFECTS OF DARKNESS ON THE REPRODUCTION OF MICE
- Examination of Myrmecophagy and Herbivory in the Madagascan Spiny-taild Iguana, Oplurus cuvieri (Reptilia: Opluridae)
- Preliminary Survey on the Turtle Community in a Lotic Environment of the Kizu River
- Sleeping Site Pattern and Sleeping Behavior of Brookesia decaryi (Chamaeleonidae) in Ampijoroa Dry Forest, Northwestern Madagascar
- Thermal Biology of an Iguanian Lizard, Oplurus cuvieri cuvieri, in a Tropical Dry Forest of Madagascar
- STUDIES ON THE REPRODUCTIVE FAILURE OF RAM CAUSED BY UNDERFEEDING III. ON THE EFFECTS OF INJECTING SALINE EMULSION OF SHEEP PITUITARY GLAND TO IMPOTENT RAM
- STUDIES ON THE ABNORMAL SPERMATOZOA I. APPEARANCE OF ABNORMAL SPERMATOZOA IN THE EXPERIMENTAL CRYPTORCHIDISM OF ALBINO RATS
- STUDIES ON THE REPRODUCTIVE FAILURE OF RAM CAUSED BY UNDERFEEDING I. ON THE EFFECTS OF UNDERFEEDlNG UPON THE MATING POTENCY OF RAM, AND THE EFFECTS OF NORMAL FEEDING UPON ITS RECOVERY FROM IMPOTENCE
- Toxicity of formaldehyde in experimental animals. Concentrations of the chemical in the elution from dishes of formaldehyde resin in some vegetables.:CONCENTRATIONS OF THE CHEMICAL IN THE ELUTION FROM DISHES OF FORMALDEHYDE RESIN IN SOME VEGETABLES
- A JOINT STUDY OF MICRODETERMINATION OF URINARY MERCURY:by investigators from three different institutes, in order to establish a standard method
- SERUM CHOLESTEROL LEVEL OF VISCOSE RAYON WORKERS
- THERAPY AND PREVENTION OF LEAD POISON-ING WITH CALCIUM VERSENATE
- CAUSATION OF OUCH-OUCH DISEASE (Itai-Itai Byo)-An Introductory Review-:PART II. EPIDEMIOLOGY AND EVALUATION
- CAUSATION OF OUCH-OUCH DISEASE (Itai-Itai Byo)-An Introductory Review:-PART I. NATURE OF THE DISEASE
- EPIDEMIC OF MERCURY POISONING IN THE AGANO RIVER AREA:An Introductory Review
- An epidemiological study on lung cancer among chromium plating workers.
- Axially dissymmetric bis(aminophosphine)s derived from 2,2'-diamino-1,1'-binaphthyl. Synthesis and application to rhodium(I)-catalyzed asymmetric hydrogenations.
- Carbon-carbon bond formation by the use of chloroiodomethane as a C1 unit. IV. The Mannich reaction of ketones by means of dihalomethane and secondary amine.
- Disease recurrence plays a minor role as a cause for retransplantation after living-donor liver transplantation for primary biliary cirrhosis : A multicenter study in Japan