RECOVERY OF MOTOR FUNCTION AND SENSORY EVOKED RESPONSES FOLLOWING BRAIN DAMAGE IN MONKEY

概要

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In the central nervous system, motor and sensory system are a convinient context in which to observe some physiological response. Additionally the rela-tionship between behavior and neurophysiological findings are easy to identify. The purpose of this paper is to clarify the mechanism of recovery of motor function after making small lesions which are small in comparison with those studied earlier. Furthermore an attempt was made to elucidate the relation-ship between motor control and sensory evoked responses. Measurements of behavioral motor function, evoked movements by brain stimulation and sensory evoked responses were taken from monkeys with array of 36 electrodes chroni-cally implanted in sensory motor cortex, before and after small electric lesion. The study was performed in two groups, the group of sensorimotor cortical damage and that of the small damage in the internal capsule. The change of three parameters showed the correlation with each other during recovery in the group 1. In the group 2, on the other hand, three parameters were not always similar in the recovery process. In the recovery of motor function, participation of the function of the area adjacent to the injured site could represent one of the important factors. Observation on sensory evoked re-sponse provided a better indicator of the recovery of motor function in the group 1 than in the group 2.
The Keio Journal of Medicineの論文