Dopaminergic modulation of the renal effect of arginine-vasopressin in water-loaded rats.
スポンサーリンク
概要
- 論文の詳細を見る
In order to confirm whether dopamine inhibits the antidiuretic action of vasopressin in mammalian kidney, we examined interactions among arginine vasopressin (AVP), dopamine and haloperidol in water-loaded ethanol anesthetized rats. The submaximal dose of AVP causing antidiuresis was 80 μU in this preparation. Dopamine at the doses of 0.11, 1.1 and 11 μg/100 g body weight (i.v.) inhibited the antidiuretic effect of 80 μU AVP by 18±7, 27±6 and 36±14%, respectively. The effect of 1.1 μg/100g body weight dopamine in inhibiting the action of AVP was completely reversed by haloperidol at 2.3 μg/100g body weight. Single administration of dopamine or haloperidol was without effect on urine flow. These observations support the view that dopamine inhibits the antidiuretic action of vasopressin by dopaminergic receptors also in the mammalian kidney.
- 公益社団法人 日本薬理学会の論文
著者
-
Sasaki Masato
Department Of Applied Chemistry Faculty Of Science And Engineering Kinki University
-
Togashi Kazutomo
Department Of Gastroenterology And Hepatology Royal Brisbane And Women's Hospital
-
Koyama Shigeru
Department Of Internal Medicine Nagano Red Cross Hospital
-
Imai Masashi
Department Of Pharmacology Division Of Molecular Pharmacology Jichi Medical University
-
TAKAHASHI Kazuhito
Department of Mechanical Engineering & Intelligent Systems, University of Electro-Communications
-
IMAI Masashi
Department of Pharmacology, National Cardiovascular Center, Research Institute
-
SETOYAMA Toshiyuki
Department of Pharmacology, Jichi Medical School
-
SUZUKI Kohki
Department of Pharmacology, Jichi Medical School
-
KAKKI Nobuyuki
Department of Pharmacology, Jichi Medical School
-
TAKAHASHI Kazuhito
Department of Pharmacology, Jichi Medical School
関連論文
- Hemorrhagic rectal ulcer caused by a deformity of the coccyx complicated by normal delivery
- Appropriate Operation for Elderly Colorectal Cancer Patients Based upon an Assessment of Preoperative Risk Factors
- Mucosal Spreading Depressed Type Colorectal Tumors : A Report of Two Cases
- Controlled Drug Release : Design and Application of New Water-soluble Prodrugs
- Acute Expression of the PRL Receptor Gene after Ovariectomy in Midpregnant Mouse Mammary Gland
- Localized giant inflammatory polyposis of the cecum associated with distal ulcerative colitis
- Effect of Probenecid and Ranitidine on Urinary Excretion of Lomefloxacin in Rats
- The use of indigocarmine spray increases the colonoscopic detection rate of adenomas
- EFFECTS OF COLLATERAL CIRCULATION ON LEFT VENTRICULAR FUNCTION IN THE PATIENTS WITH ACUTE MYOCARDIAL INFARCTION : Myocardial Infarction : 53 Annual Scientific Meeting, Japanese Circulation Society
- Thymic mucosa-associated lymphoid tissue lymphoma associated with bilateral orbital pseudotumor
- Prevalence of Synchronous Colorectal Neoplasms Detected by Colonoscopy in Patients with Gastric Cancer
- Mucinous Cystadenocarcinoma of the Appendix Invading the Ascending Colon with Fistula Formation : Report of a Case
- Pathological Predictors for Lymph Node Metastasis in T1 Colorectal Cancer
- DIAGNOSIS OF NEOPLASTIC CHANGES BY MAGNIFYING COLONOSCOPY IN A PATIENT WITH CRONKHITE-CANADA SYNDROME : A CASE REPORT
- Significance of Periappendiceal Inflammation in the Patients with Distal Ulcerative Colitis
- Transferrin Is Not Involved in the Entry of^Ga into Hepatocytes from Regenerating Liver of Partially Hepatectomized Rats
- The Facile Preparation, Crystal Structure, and Chemical and Electrochemical Properties of 9-Anthryl-3-guaiazulenylmethylium Hexafluorophosphate
- "O-Acyl Isopeptide Method" for the Synthesis of Difficult Sequence-Containing Peptides : Application to the Synthesis of Amyloid β Peptide (Aβ) 1-42
- Preparation of a Binuclear Oxo(tropolonato)molybdenum(V) Complex and Its Spectroscopic Properties and Crystal Structure
- A Facile Preparation and Properties of (2E, 4E, 6E, 8E)-1-(3-Guaiazulenyl)-3, 7-dimethyl-9-(2, 6, 6-trimethyl-1-cyclohexen-1-yl)-2, 4, 6, 8-nonatetraen-1-ylium Hexafluorophosphate
- A Facile Preparation of 5-Isopropyl-idene-3,8-dimethyl-1(5H)-azulenone and Its Crystal Structure
- Preparation and Characteristic Properties of 1,4-Bis(3-guaiazulenylmethylium)benzene Bishexanuorophosphate
- Bicriteria Knapsack Problem with GUB Structure by Hybrid Genetic Algorithm
- A Novel Method for the Synthesis of Difficult Sequence-Containing Peptides via O-Acyl Isopeptides : The Use of O-N Intramolecular Acyl Migration Reaction
- Structure and Expression of a Murine Homologue of sky Receptor Tyrosine Kinase Gene
- Intrarenal Localization of Receptors for α-Rat Atrial Natriuretic Polypeptide: An Autoradiographic Study with [125I]-Labeled Ligand Injected in Vivo into the Rat Aorta
- Mechanism of iodide transport in the rabbit cortical collecting duct
- Morphological and functional heterogeneity of the thick ascending limb of Henle's loop
- Analysis of Major Virulence Factors in Porphyromonas gingivalis under Various Culture Temperatures Using Specific Antibodies
- VIRTUAL ENTEROSCOPY USING AIR AS THE CONTRAST MATERIAL : A PRELIMINARY FEASIBILITY STUDY
- Welcome to Clinical and Experimental Nephrology
- ファジィ De Novo 計画に基づく信頼性最適化問題の遺伝的アルゴリズムによる一解法
- A Pilot Study on Using the Patient Health Questionnaire in the Primary Care Setting in Japan
- Suppression of Flatness in Circular Tube-Draw Bending by Applying Side Compression
- Development of a Tube-Spinning Machine for Thin Tubes with a Large Diameter
- Intestinal strangulation caused by a mucocele of the appendix : report of a case
- Dopaminergic modulation of the renal effect of arginine-vasopressin in water-loaded rats.