下顎骨に発生した放射線誘発骨肉腫の1例

概要

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A case of a 54-year-old male patient, who developed osteosarcoma in the mandible 25 years after the combined treatment of surgery and interstitial radium and external radiation therapy for lingual cancer, was reported. In the Japanese literature only one case of radiation-induced osteosarcoma arising in the mandible was found. The patient was admitted to Hokkaido University Hospital with a complaint of painful mass in the right half of the mandibular body in March, 1981. On physical examination a rough surfaced firm tumor was located in the lateral aspect of the midportion of the mandibular body. A roentogenogram of the mandible revealed an osteolytic lesion. Hemimandibular resection combined with radical neck dissection was performed in May, 1981. The histological examination of the resected specimen showed osteosarcoma with marked osteoid formation and no lymph node metastasis was revealed. The patient remains alive with no evidence of recurrence or metastasis.
社団法人日本耳鼻咽喉科学会の論文