内耳疾患薬物療法の実験的根拠 : 特に Meclofenoxate hydrochlorideについて

概要

論文の詳細を見る
To make an assay whether or not a medicament has an actual value for bringing in the doubie blind test of inner ear diseases, an experimental design was presented: 1. Recording of cochlear microphonics (CM) from the basal turn of the cochlea of guinea pigs, 2. Observation of the change in the amplitude of CM by applying NaCl crystals on the round window membrane 3.Observation of change of CM after applying both the medicament and Nacl crystals. 4. Statistical comparison of the resuls.Meclophenoxate hydrochloride was used as a medicament in this study. This medicament had shown a significant effect in decreasing the NaCl-effects on CM. It seems worthwhile to utilize Meclophenoxate hydrochloride for the double blind test in the inner ear disease.
社団法人日本耳鼻咽喉科学会の論文