猫,モルモットの第8脳神経切断の蝸牛内諸電位に及ぼす影響に関する研究

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The author reported on changes in the AP. CM. SP. of cats and, guinea pigs for the several days following the section of the 8th nerve at the entrance of the internal auditory meatus. Cats and guinea pigs were anesthetized with nembut- al. The chief results were as follows: 1) The electrical responses of the neural com- ponents to click could be recorded for 10 days af- ter the section of the 8th nerve without disturbing blood supply. 2) The latency of AP. Nt after the section showed no significant change compared with that before the section. 3) Immediately after the section the ampli- tude of AP. N1N2 increased to 165%, and subseq- uently reduced to 84% after 12 hours. 4) The biphasic deflection of AP was recor- ded at the entrance of the internal auditory mea- tus. 5) A slow negative potential appeared bet- ween N1 and N2 of AP., with lower intensity es- pecially-30 db. 6) AP. N1 was able to be recorded for 69 hours on an average and disappeared completely after 72 hours. 7) CM. and SP. were able to be recorded for 10 days after the section. No remarkable changes were observed in the amplitude of CM after the section. 8) In order to experiment in a short time, guinea pigs were used whose 8th nerve was sec- tioned tbrouth the cerebellum. The wave form of AP changed immediatly after the section as same as in case of cats.
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