Lifestyles and Pre-eclampsia with Special Attention to Cigarette Smoking
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概要
- 論文の詳細を見る
Cigarette smoking has been reported to protect women against pre-eclampsia. We conducted a cohort study of 493 women whose first antenatal visits were between September 1997 and April 1998 at Osaka Prefectural General Hospital, Japan. A self-administered questionnaire survey for lifestyles was carried out during pregnancy, and pregnancy outcome information was taken from medical record data. Of 493 subjects, 82 cases (16.6%) developed mild pre-eclampsia and 3 cases (0.6%) developed severe one. The prevalence of cigarette smokers decreased from 21.3% to 8.6% during early pregnancy. The incidence rate of pre-eclampsia among smokers was slightly greater than that among nonsmokers (19.4% vs 17.1%), the incidence rate among cases exposed from household smoking was greater than that among no exposed cases (19.6% vs 14.3%), and the incidence rate among alcoholdrinkers was greater than that among non-drinkers (21.1 % vs 15.1 %). However, there were no statistically significant differences. Larger body mass index before pregnancy tended to be associated with the increased incidence rate of pre-eclampsia (p=0.160). Pregnant women with smoking had a statistically higher frequency of household smoking exposure and having drinking alcohol. Household smoking exposure and drinking alcohol status adjusted hazard rate ratio was 1.1 for smokers (95% confidence interval 0.6-1.7) as compared with that for non-smokers. Our results did not support the proposition that cigarette smoking protected women against pre-eclampsia. J Epidemiol2003;13:90-95.
- 日本疫学会の論文
著者
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Ioka Akiko
Department Of Obstetrics And Gynecology Osaka Prefectural General Hospital
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Nakamuro Karo
Department Of Obstetrics And Gynecology Osaka Prefectural General Hospital
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Tsukuma Hideaki
Department Of Cancer Control And Statistics Osaka Medical Center For Cancer And Cardiovascular Disea
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Ioka Akiko
Department Of Cancer Control And Statistics Osaka Medical Center For Cancer And Cardiovascular Disea
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