Optimization of L-aspartic acid production using immobilized Escherichia coli cells without regard to decay of aspartase activity.

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概要

• 論文の詳細を見る

• This article describes an efficient production method for L-aspartic acid using aspartase activity of immobilized Escherichia coli cells. The method was examined by use of a rate equation for the aspartase reaction derived on the basis of a one-substrate, one-product mechanism of enzyme reaction. It was found that the reaction temperature must be decreased with the progress of the reaction to obtain higher conversion efficiently near the end of the reaction. In addition, the productivity of L-aspartic acid was found to be increased with an increase in input substrate concentration.

• 公益社団法人 化学工学会の論文

著者

• Yamashita Kiyokazu

  Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.

• Takamatsu Satoru

  Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.

• YAMASHITA KIYOKAZU

  Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Co., Ltd.

関連論文

• Kinetics of Production of _L-Aspartic Acid by Aspartase of Immobilized Escherichia coli Cells
• Industrial production of L-alanine from ammonium fumarate using immobilized microbial cells of two kinds.
• Optimization of L-aspartic acid production using immobilized Escherichia coli cells without regard to decay of aspartase activity.

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