Kinetics of Production of _L-Aspartic Acid by Aspartase of Immobilized Escherichia coli Cells

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概要

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• For the control of aspartase production and for the design of a reactor using immobilized Escherichia coli cells, a simple and useful equation was derived. In a continuously stirred tank reactor the rate equation was shown to sufficiently satisfy the experimental results obtained with several input concentrations of fumaric acid. Kinetic constants of the rate equation obtained, however, were found to be altered by changing of the input concentration of fumaric acid. This phenomenon may result from the change of diffusibility of fumaric acid and _L-aspartic acid in gel matrices depending on the structural change of polyacrylamide gel caused by the variation of the input concentration of fumaric acid. Then the kinetic constants were represented as the function of the input concentration of fumaric acid.

• 公益社団法人日本生物工学会の論文
• 1980-04-25

著者

• Yamashita Kiyokazu

  Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.

• Sumi Akihiko

  Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co Ltd.

• Takamatsu Satoru

  Research Laboratory Of Applied Biochemistry Tanabe Seiyaku Co. Ltd.

関連論文

• Kinetics of Production of _L-Aspartic Acid by Aspartase of Immobilized Escherichia coli Cells
• Industrial production of L-alanine from ammonium fumarate using immobilized microbial cells of two kinds.
• Optimization of L-aspartic acid production using immobilized Escherichia coli cells without regard to decay of aspartase activity.

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