A study on the histological classification of large bowel mucinous carcinoma. Examination of the ratio of the area containing mucous nodule.:-Examination of the Ratio of the Area Containing Mucous Nodule-

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To examine the histological classification of large bowel mucinous carcinoma, the ratio of the area of mucous nodules histologically characteristic of large bowel mucinous carcinoma, to the area of the entire carcinoma was calculated with a digitizer. 281 cases of large bowel carcinoma including well, moderately, and poorly differentiated adenocarcinoma, and mucinous carcinoma were examined. The results were then compared with the histological classification obtained by conventional microscopy alone. <BR>Mucous nodules were observed in 85 cases (30.2 %), and in 42 of these, the ratio of the area of mucous nodule to the whole was less than 10 %. Although there were 17 cases with a ratio of 50 % or more which should be diagnosed as mucinous carcinoma according to the General Rules for Clinical and Pathological Studies on Cancer of Colon, Rectum and Anus, only 10 cases were classified as mucinous carcinoma. Of the remaining 7 cases, 5 were classified as well differentiated adenocarcinoma, and 2 as moderately differentiated adenocarcinoma. Since the area ratio of mucous nodules in these 7 cases was between 50 % and 70 % levels, it was proved to be sometimes difficult to judge the predominant histological type in terms of the area by microscopy alone.
日本大腸肛門病学会の論文