Clinical studies on autonomic nerve preserving operation for rectal cancer.

概要

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Ninety six cases of rectal cancer were treated curatively by autonomic nerve preserving operation from March 1982 to December 1985. Clinical results of nerve preserving operation were compared with those of extensive lymphnode dissection. The cumulative 5-year-survival rate of nerve preserving operation was 73.5 %, and that of extensive lymphnode dissection was 64.2 %. Clinicopathologic feature of the cancer had no significant influence on 5-year-survival rate or rate of local recurrence after nerve preserving operation. Therefore, radicality of nerve preserving operation was considerd to be equal to that of extended lymphnode dissectioon. But, local recurrence rate of cases with positive lymphnode metastasis and moderately differentiated adenocarcinoma were significantly higher than the rate of cases with negative lymphnode metastasis and well differentiated adenocarcinoma. It was considered, therefore, that such cases should be excluded from indication for nerve preserving operation. <BR>In cases with well differentiated adenocarcinoma, negative lymphnode metastasis and depth of invasion limited to ss al, the retrospective cumulative 5-year-survival rate of nerve preserving operation was 83.3 %, and the did not decrease significantly, compared with extensive lymphnode dissection in cases of the same clinicopathologic features.
日本大腸肛門病学会の論文