A study of treatment for liver metastasis of colorectal carcinoma.

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Of 196 patients who underwent resection of colorectal carcinoma in our department during the 5 years from 1983 to 1987, 35 with liver metastasis (synchronous in 25 and metachronous in 10) were analyzed with special reference to the therapy employed. <BR>Among patients with synchronous liver metastasis, hepatectomy was performed in 4, transcatheter therapy in 11 and chemotherapy in 10, whereas among those with metachronous metastasis, hepatectomy was performed in 4, transcatheter therapy in 5 and chemotherapy in 1. <BR>Mean survival in synchronous cases was 16 months in the hepatectomy group, 13 months in the transcatheter therapy group and 7 months in the chemotherapy group. On the other hand, in the metachronous cases, mean survival was 20 months in the hepatectomy group, 11 months in the transcatheter therapy group and 4 months in the chemotherapy group. <BR>Recurrence of carcinoma in the remaining liver after hepatectomy was found in 2 of 4 patients with synchronous metastasis and in all 4 with metachronous metastasis. In contrast, no such recurrence has been noted to date in 2 of 4 patients who received continuous intra-arterial infusion chemotherapy following hepatectomy.
日本大腸肛門病学会の論文