直腸肛門部悪性黒色腫の2例

概要

論文の詳細を見る
Two cases of anorectal malignant melanoma are reported with a brief discussion of the tumor nuclear DNA content. Case 1 was a 66-year-old woman with anal pain. Proctoscopy showed a black tumor of the anal canal. Case 2 was a 68-year-old woman with anal itching. Proctoscopy showed a pale red tumor of the anal canal. Abdomino-perineal resection was performed in both cases, and the histological findings of the surgical specimens were malignant melanoma. In both cases, the tumor nuclear DNA histograms showed aneuploidy. Many investigators have reported that the tumor nuclear DNA content in cancers may be an important prognostic factor and that aneuploid cases have a worse prognosis than diploid cases. However, we were unable to find any report about the relationship between anorectal malignant melanoma and tumor nuclear DNA ploidy. In the future, this aspect will require investigation.
日本大腸肛門病学会の論文