Progressive Systemic Sclerosis Complicated with Immune Thrombocytopenia during D-penicillamine Therapy.
スポンサーリンク
概要
- 論文の詳細を見る
Immune thrombocytopenia is a rare complication of progressive systemic sclerosis (PSS). A 47-year-old female with PSS treated with D-penicillamine developed immune thrombocytopenia, which promptly responded to prednisolone and withdrawal of D-penicillamine. Platelet-associated IgG was elevated and the bone marrow megakaryocyte count was normal. There was an inverse relationship between the level of platelet-associated IgG and the platelet count. A lymphocyte stimulation test sensitized by D-penicillamine was positive. The present case suggests that immunethrombocytopenia may be regarded as one of the D-penicillamine-related immune abnormalities. To our knowledge, its association with PSS has never been reported.(Internal Medicine 31 : 244-245, 1992)
- 社団法人 日本内科学会の論文
著者
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TAKEMURA HIROYUKI
Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba
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YAMANE KAZUHIDE
Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba
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KASHIWAGI HEIHACHIRO
Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba
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Kato Shinjiro
Department Of Chemical Engineering Faculty Of Engineering
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Takemura Hiroyuki
Department Of Chemical And Biological Science Faculty Of Science Japan Women's University
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Kashiwagi Heihachiro
Department Of Internal Medicine University Of Tsukuba
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Suzuki Hiroshi
Department Of Allergy And Immunology National Research Institute For Child Health & Development
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Sakauchi Michihiro
Department Of Internal Medicine Kasumigaura National Hospital
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NATSUDA Hiromiki
Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba
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MATSUI Yoshiki
Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba
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KONO Ichiro
Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba
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Kono Ichiro
Department of Comprehensive Human Sciences, Tsukuba University
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