Portal-Systemic Encephalopathy and Hypothalamic Hypothyroidism: Effect of Thyroid Hormone on Ammonia Metabolism.

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概要

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• We describe a 53-year-old woman with portal-systemic encephalopathy and altered thyroid function. Endocrinological studies revealed low levels offree thyroid hormone with an inappropriately low level of thyroid-stimulating hormone that responded to bolus injection of thyrotropinreleasing hormone with a normal but somewhat delayed pattern. On the diagnosis of hypothalamic hypothyroidism, she was treated with levothyroxine sodium. Thyroid hormone replacement improved not only the symptoms of hypothyroidism but the hyperammonemiaand consciousnessdisturbance, which suggested a hitherto undescribed possibility that hypothyroidism may be an exacerbation factor of hyperammonemia and portal-systemic encephalopathy.(Internal Medicine 32: 655-658, 1993)

• 社団法人　日本内科学会の論文

著者

• Sakuta Manabu

  The Department Of Neurology Japanese Red Cross Medical Center

• TERAO Yasuo

  the Department of Neurology, Japanese Red Cross Medical Center

• HITOSHI Seiji

  the Department of Neurology, Japanese Red Cross Medical Center

関連論文

• Mexiletine for Painful Alcoholic Neuropathy
• Portal-Systemic Encephalopathy and Hypothalamic Hypothyroidism: Effect of Thyroid Hormone on Ammonia Metabolism.
• Elevated Serum Interleukin-6 in POEMS Syndrome Reflects the Activity of the Disease.

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