Mexiletine for Painful Alcoholic Neuropathy
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概要
- 論文の詳細を見る
Five patients suffering from painful alcoholic neuropathy showed severe painful sensory disturbance in their extremities. Although their pain was not ameliorated by the typical usual analgesic agents, oral mexiletine (MX) therapy was remarkably effective for the pain (especially tingling and aching sensation) without major side effects. This study indicated that the minimum effective dose was 300 mg per day and the effective concentration of MX in plasma was 0.66±0.15 μg/ml in these patients. Thus, oral MX therapy can be a reliable treatment for pain in alcoholic neuropathy.(Internal Medicine 34: 577-579, 1995)
- 社団法人 日本内科学会の論文
著者
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Sakuta Manabu
The Department Of Neurology Japanese Red Cross Medical Center
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Nishiyama Kazutoshi
The Department Of Neurology Institute For Brain Research School Of Medicine University Of Tokyo
関連論文
- Mexiletine for Painful Alcoholic Neuropathy
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