1. Hypertension and Genes
スポンサーリンク
概要
- 論文の詳細を見る
Under classical strategy, scientists have tried first to find a physiological phenomenon specific for essential hypertension, then to identify the protein underlying the physiological abnormality, and finally to clarify the causative gene which encoded the protein. On the other hand, under the reverse genetic approach, the correlation between hypertension and genetic abnormality is identified first, and then the pathogenesis is clarified-in reverse order. Therefore, it is not extraordinary for unexpected results to be obtained in the correlation between a gene and a disease, suggesting that this approach has a possibility to be a breakthrough in the chaos of hypertension research.
- 社団法人 日本内科学会の論文
著者
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Morishita Ryuichi
the Department of Geriatric Medicine, Keio University School of Medicine
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Higaki Jitsuo
the Department of Geriatric Medicine, Keio University School of Medicine
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Ogihara Toshio
The Department Of Geriatric Medicine Osaka University Medical School
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Morishita Ryuichi
Division Of Gene Therapy Science Osaka University Graduate School Of Medicine
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Katsuya Tomohiro
The Department Of Geriatric Medicine Osaka University Medical School
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HIGAKI Jitsuo
The Department of Geriatric Medicine, Osaka University Medical School
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Ogihara Toshio
The Department of Geriatric Medicine, Osaka University Medical School
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KATSUYA Tomohiro
The Department of Geriatric Medicine, Osaka University Medical School
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MORISHITA Ryuichi
The Department of Geriatric Medicine, Osaka University Medical School
関連論文
- Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats
- Genetic basis of hypertension for the development of tailored medicine
- OE-071 A Genom-Wide Association Study of SNPs in the risk of Atherosclerosis Obliterans(Heart failure, clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- DPJ-013 Hepatocyte Growth Factor Attenuates TGF-β1 Angiotensin II Crosstalk by Down Regulation of Angiotensin II Type 1 Receptor through PTEN/Akt Pathway(DPJ03,Kidney/Renal Circulation/CKD (H),Digital Poster Session (Japanese),The 73rd Annual Scientific M
- Catheter-Delivered In Vivo Gene Transfer into Rat Myocardium Using the Fusigenic Liposomal Mediated Method
- Association of Mast Cell Chymase Gene Variant with HDL Cholesterol, but not with Blood Pressure in the Ohasama Study
- Variation in OSBPL10 is associated with dyslipidemia
- Serum hepatocyte growth factor concentration is a specific marker of endothelial dysfunction in humans
- Association of Serum Oxidized Lipoprotein(a) Concentration with Coronary Artery Disease : Potential Role of Oxidized Lipoprotein(a) in the Vasucular Wall
- PJ-042 Pivotal Roles of CYLD (cylindromatosis) as a Deubiquitinating Enzyme in Vasculature(Atherosclerosis, basic(05)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)