Pulmonary Lymphangioleiomyomatosis; Unusual Radiological Manifestation of Multiple Large Nodules.
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概要
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A 44-year-old woman was admitted to our hospital in August 1999 for multiple large nodules detected on chest roentgenogram in an annual health check. Chest CT scans showed bilateral large nodules (>10 mm in diameter) with irregular margins and multiple thin walled cystic lesions. From these radiologic examinations, we suspected pulmonary Langerhans cell histiocytosis. Histological examination of the biopsy specimen by video-assisted thoracoscopy revealed a marked proliferation of the spindle cells, which were immunologically positive for alpha-smooth muscle actin and HMB-45, in the cyst walls and lung parenchyma. The large nodules consisted of proliferation of the smooth muscle cells surrounded by a dense layer of hemosiderinladen macrophages. During the two years subsequent to these 1999 examinations, the opacities have gradually diminished and the patient was found to have pulmonary lymphangioleiomyomatosis. This case exhibited rare radiologic manifestations of multiple large nodules mimicking Langerhans cell histiocytosis.(Internal Medicine 41: 879-882, 2002)
- 社団法人 日本内科学会の論文
著者
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ABE Shosaku
the Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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SATOH Masaaki
the Department of Clinical Pathology, Sapporo Medical University School of Medicine
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SUZUKI Kazuhiko
the Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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SHIRATORI Masanori
the Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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YAMADA Gen
the Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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ITOH Takayuki
the Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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TANAKA Shintaro
the Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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Yamada Gen
The Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Nagata Manabu
The Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Saizen Hitoki
The Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Shiratori Masanori
The Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Tanaka Shintaro
The Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Abe Shosaku
The Third Department Of Internal Medicine
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Tanaka Hiroshi
The Third Department Of Internal Medicine And The Department Of Medical Information Hamamatsu Univer
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ITOH Takayuki
the Third Department of Internal Medicine, Kansai Medical University
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