Peripheral Primitive Neuroectodermal Tumor of the Chest Wall of a 69-year-old Man
スポンサーリンク
概要
- 論文の詳細を見る
We report a case of peripheral primitive neuroectodermal tumor (pPNET), which belongs to the pPNET/Ewing’s sarcoma family, arising in the chest wall of a 69-year-old man. He had high levels of serum neuron-specific enolase and pro-gastrin-releasing peptide, which are believed to be useful diagnostic blood markers for small cell lung carcinoma (SCLC). Microscopically, the tumor was composed of solid nests and sheets of monotous, primitive, small round cells with a few rosettes, making it difficult to distinguish from SCLC. Immunohistochemically, the tumor cells showed intense cell membranous immunoreactivity for MIC2 protein (CD99). EWS/FLI-1 chimeric mRNA that originated from the characteristic t(11;22)(q24;q12) chromosomal translocation was detected by RT-PCR and nucleotide sequence analysis. These results confirmed the diagnostic validity of the present tumor being a pPNET, thus raising the possibility that in the past, pPNETs which have arisen in the chest have been mistakenly diagnosed as SCLC.
- 社団法人 日本内科学会の論文
- 2004-07-01
著者
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Itoh Takayuki
Department Of Cardiology Aichi Medical University
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Ikeda Tatsuru
Department of Clinical Pathology, School of Medicine, Sapporo Medical University
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SAIKAI TOYOHIRO
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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Abe Shosaku
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Itoh Takayuki
Department Of Respiratory Medicine Sapporo Hospital Hokkaido Railway Company
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Tanaka Hiroshi
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Kimura Sachiko
Department of Clinical Pathology, Sappro Medical University School of Medicine
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TAKAGI (TAKAHASHI)
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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SHIJUBO Noriharu
Department of Respiratory Medicine, Sapporo Hospital, Hokkaido Railway Company
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YAMADA Gen
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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SAITOH Eri
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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SAWADA Kaku
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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OHNISHI Tetsuro
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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TAKAHASHI Hiroki
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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Yamada Gen
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Yamada Gen
The Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Ikeda Tatsuru
Department Of Pathology Sapporo Medical University School Of Medicine
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Ikeda Tatsuru
Department Of Clinical Pathology Sapporo Medical University School Of Medicine
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Saitoh Eri
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Sawada Kaku
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Kimura Sachiko
Department Of Pathology Sapporo Medical University School Of Medicine
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Takagi (takahashi)
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Saikai Toyohiro
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Ohnishi Tetsuro
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Shijubo Noriharu
Department Of Respiratory Disease Sapporo Hospital Hokkaido Railway Co.
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Shijubo Noriharu
Department Of Respiratory Medicine Sapporo Hospital Hokkaido Railway Company
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Shijubo Noriharu
Department Of Pathology Sapporo Medical University School Of Medicine
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Itoh Takayuki
Department Of Applied Physics Waseda University
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Abe Shosaku
The Third Department Of Internal Medicine
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Takahashi Hiroki
Third Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Takagi-Takahashi Yoko
Third Department of Internal Medicine, Sapporo Medical University School of Medicine
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KIMURA Sachiko
Department of Cardiology, Koshigaya Hospital, Dokkyo University School of Medicine
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