Prevalence of Hyperesthesia Detected by Current Perception Threshould Test in Subjects with Glucose Metabolic Impairments in a Community
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概要
- 論文の詳細を見る
Objective Recent studies reported that hyperesthesia may be an indicator of early diabetic polyneuropathy. Using the current perception threshold (CPT) test, which stimulates peripheral sensory nerve fibers by three different frequencies (2, 000, 250, and 5 Hz), we investigated the relationship between hyperesthesia and glucose metabolic impairment in a community. Methods The number of subjects, aged 40 to 79 years, was 2, 074. The CPT values at each frequency were classified into three categories (hyperesthesia, normal, and hypoesthesia). Subjects were also subgrouped into three groups (normal, insulin resistance, and diabetes) according to glucose metabolic status, and those with hypoesthesia at each frequency were excluded in the analyses. Results The prevalence of hyperesthesia at 2, 000, 250, and 5 Hz in male diabetic subjects were 14.1, 15.6, and 7.7%, respectively, and 22.2, 24.5, and 16.4% respectively in female diabetic subjects. In logistic regression analysis adjusted for age, females with diabetes showed a significantly high odds ratio (OR) for hyperesthesia at 2, 000 Hz (OR, 2.42; 95% confidence interval (95%CI), 1.18 to 4.97) and 250 Hz (OR, 2.65; 95%CI, 1.31 to 5.37). In male diabetic subjects, a significantly high odds ratio for hyperesthesia was seen at 250 Hz (OR, 2.09; 95%CI, 1.07 to 4.05). Conclusion Our results suggested that hyperesthesia may emerge coupled with developing diabetes, supporting the precedent hypothesis.(Internal Medicine 41:1124-1129, 2002)
- 社団法人 日本内科学会の論文
- 2002-12-01
著者
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NIINO Naoakira
Department of Epidemiology, National Institute for Longevity Sciences
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Niino N
Department Of Epidemiology National Institute For Longevity Sciences
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Ando Fujiko
Department Of Epidemiology National Institute For Longevity Sciences National Center For Geriatrics
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Shimokata H
Department Of Epidemiology National Institute For Longevity Sciences National Center For Geriatrics
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Shimokata Hiroshi
Department Of Epidemiology And Social Medicine Research Institute For Nuclear Medicine And Biology H
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TAKEKUMA Kiyoshi
Department of Public Health, Nagoya City University Medical School
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Takekuma Kiyoshi
Department Of Public Health Nagoya City University Medical School
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TAKEKUMA Kiyoshi
Department of Epidemiology, National Institute for Longevity Sciences
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Shimokata Hiroshi
Department for Development of Preventive Medicine, National Center for Geriatrics and Gerontology
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