Acetazolamide-induced Muscle Weakness in Hypokalemic Periodic Paralysis
スポンサーリンク
概要
- 論文の詳細を見る
A 46-year-old man with hypokalemic periodic paralysis (HypoPP) and diabetes mellitus (DM) had worsened muscle weakness after acetazolamide (ACZ) treatment. During the paralytic episode, serum potassium levels were reduced, and serum chloride and insulin levels were increased. The data suggested proximal renal tubular acidosis due to ACZ. We determined arterial-venous concentrations of potassium, insulin and glucose across the forearm. Venous potassium levels were markedly reduced. ACZ is thought to potentiate potassium uptake into muscles. Hyperinsulinemia and DM could contribute to ACZ-induced exacerbation in our patient. We should pay more attention to ACZ-treated HypoPP patients with hyperinsulinemia and DM.(Internal Medicine 41: 743-745, 2002)
- 社団法人 日本内科学会の論文
- 2002-09-01
著者
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Kinoshita Masao
The Fourt Department Of Internal Medicine Toho University Ohashi Hospital
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Ikeda Ken
The Department Of Neurology Division Of Brain Check-up Pl Tokyo Health Aew Center
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Igarashi Osamu
Department Of Neurology Toho University Omori Hospital
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Ichikawa Yasumitsu
The Fourt Department Of Internal Medicine Toho University Ohashi Hospital
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SATOYOSHI Eijiro
Department of Neurology, Toho University Ohmori Hospital
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Ikeda Ken
Department Of Neurology Toho University Omori Hospital
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Iwasaki Yasuo
Department Of Neurology Toho University Omori Hospital
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Iwasaki Yasuo
Department Of Neurology Toho University Ohmori Hospital
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Iwasaki Yasuo
The Fourt Department Of Internal Medicine Toho University Ohashi Hospital
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Satoyoshi Eijiro
The Fourt Department Of Internal Medicine Toho University Ohashi Hospital
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Yabuki Daisuke
The Fourt Department Of Internal Medicine Toho University Ohashi Hospital
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IGARASHI Osamu
the Fourt Department of Internal Medicine, Toho University Ohashi Hospital
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SATOYOAHI Eijiro
the Fourt Department of Internal Medicine, Toho University Ohashi Hospital
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Ikeda Ken
Department Of Neurology Division Of Brain Check-up Pl Tokyo Health Care Center
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