Vectorcardiography in Experimental Myocardial Infarction. Serial Changes and Correlation between QRS Loop Change and the Infarction Size.:Serial Changes and Correlation between QRS Loop Change and the Infarction Size
スポンサーリンク
概要
- 論文の詳細を見る
The objectives of this study were to examine the serial vectorcardiographic changes following acute myocardial infarct and to assess the relationship between QRS loop changes and infarct size. Fifty adult male Long-Evans rats of 250-350gm body weight were used to study experimental acute myocardial infarction induced by coronary artery ligation. Vectorcardiograms (VCG) of the Frank lead system were recorded before, and 1 day and 7 days after operation. Animals were sacrificed on the 7th day for histological quantitation of infarct area ratios. We found that (1) before operation, rats have ST elevation, probably due to early repolarization. (2) After coronary artery ligation, ECG showed characteristic dome-shaped ST elevation at 1hr after ligation which returned to normal during the first day. Abnormal Q waves appeared thereafter. (3) After ligation, maximum QRS vector, ST vector and maximum T vector were reduced in magnitude the first day and recovered by the 7th day. The vectors tended to shift their direction to the right and to the posterior. QRS-T angle, however, widened as time went on. About half of the rats revealed changes in the inscription direction of the QRS loop and abnormal QRS morphology also appeared in about half of the ligated rats. (4) Those in whom abnormal QRS loop morphology and/or biting appeared had signifi-cantly larger infarct area ratios (p<0.01). (5) Change in QRS loop inscription direction seemed not to be related to the infarct size. (6) In the LS plane, the difference in max QRS vector magnitude between the 1st and 7th days significantly correlated with the infarct area ratio (r=0.533, p<0.05). In the H plane, the change in the max QRS vector magnitude at the 7th day correlated with the infarct area ratio (r=-0.531, p<0.05). In the F plane, changes in the direction of the max QRS vector were significantly correlated to the infarct area ratio both on the first (r=0.431, p<0.05) and 7th days (r=0.531, p<0.05). It is concluded that the VCG, like the ECG, had evolutional changes in AMI and that the QRS loop seen on vectorcardiography has only a slight correlation with the histological myocardial infarct size.
- International Heart Journal刊行会の論文
著者
-
Wu Teh-lu
Department Of Internal Medicine National Taiwan University Hospital
-
Hsu Kwan-lih
Department Of Internal Medicine E-da Hospital
-
TSENG Yung-Zu
Department of Internal Medicine, College of Medicine, National Taiwan University
-
TSENG Chuen-Den
Department of Internal Medicine, College of Medicine, National Taiwan University
-
CHIANG Fu-Tien
Department of Internal Medicine
-
CHIANG Fu-Tien
Department of Internal Medicine, National Taiwan University Hospital
-
Lo Huey-Ming
Department of Internal Medicine
-
CARSON Wangden
Department of Internal Medicine, National Taiwan University Hospital
-
TSENG Chuen-Den
Department of Internal Medicine
-
HSU Kwan-Lih
Department of Internal Medicine
-
Tseng Yung-Zu
Department of Cardiology, Show-Chwan Memorial Hospital
関連論文
- Interaction of ADIPOQ Genetic Polymorphism With Blood Pressure and Plasma Cholesterol Level on the Risk of Coronary Artery Disease
- Cardiac Contractility in Noninsulin Dependent Diabetes Mellitus Evaluated Using the Relation between Endsystolic Wall Stress and Velocity of Circumferential Fiber Shortening
- Additional Data on Body Surface Potential Maps of Ventricular Repolarization in Normal Adults
- HEMIBLOCK IN ACUTE MYOCARDIAL INFARCTION : (Part III)
- Continuous intravenous infusion of prostaglandin E1 improves myocardial perfusion reserve in patients with ischemic heart disease assessed by positron emission tomography : a pilot study
- The Cause-Effect Relationship of Sympathovagal Activity and the Outcome of Percutaneous Transluminal Coronary Angioplasty
- The Use of Body Surface Potential Map for Identifying Sites of Accessory Pathway in Patients with Wolff-Parkinson-White Syndrome.
- Vectorcardiography in Experimental Myocardial Infarction. Serial Changes and Correlation between QRS Loop Change and the Infarction Size.:Serial Changes and Correlation between QRS Loop Change and the Infarction Size
- Body Surface Potential Maps of Ventricular Depolarization in Normal Adults.
- Right ventricular ejection fraction validation of first-pass radionuclide studies by contrast angiography.:Validation of First-Pass Radionuclide Studies by Contrast Angiography
- Myocardial Mechanics and Titin in Experimental Insulin-resistant Rats.
- Characteristic Findings of Body Surface Potential Map during Ventricular Repolarization in Patients with Coronary Heart Disease.
- Lack of Association between Angiotensin-converting Enzyme Gene Polymorphism and Coronary Heart Disease in a Chinese Population.
- 11. Urinary 17-ketosteroids in liver disease and experimental study of compound S test (a liver function test)
- Stent Graft Used to Rescue Coronary Rupture during Percutaneous Coronary Intervention for Myocardial Bridge