Postprandial Hemodynamic Changes Evaluated by a Doppler Echocardiographic Method.
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概要
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To evaluate postprandial hemodynamic changes, Doppler measurements of stroke volume before and after lunch were carried out in 10 healthy volunteers (all men) with a mean age of 28 years. The stroke volume was calculated as the product of echocardiographically determined aortic valve area and the ejection flow velocity integral obtained by continuous wave Doppler. The stroke volume before lunch was 61±7ml, which was increased to 72±8ml 1 hour after lunch and remained constant for the next 4 hours. Five hours later the stroke volume was then decreased to the baseline. M-mode echocardiography revealed an increase in left ventricular end-diastolic dimension and ejection fraction after lunch.Another 9 healthy subjects (6 women and 3 men) with a mean age of 52 years received a 75g oral glucose tolerance test (OGTT) instead of a common lunch; stroke volumes were not altered in association with the elevation of plasma glucose level.In conclusion, ingestion of food had a positive inotropic effect and caused circulating blood volume expansion with an increment of heart rate. Therefore, Doppler studies that are not standardized for patients' mealtimes may affect the validity of data in serial studies of left ventricular function.
- International Heart Journal刊行会の論文
著者
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Marumo Fumiaki
Second Department Of Internal Medicine Faculty Of Medicine Tokyo Medical And Dental University
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TAKASU Nobuyuki
The Second Department of Internal Medicine, Faculty of Medicine, The University of Ryukyus
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Takamoto Toshihiko
Second Department Of Internal Medicine Tokyo Medical And Dental University
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Nitta Masao
Second Department Of Internal Medicine Tokyo Medical And Dental University
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MURAKAMI KEIJI
The Second Department of Internal Medicine, Kobe University School of Medicine
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ISHIMINE Michiko
The Second Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
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TAKASU Nobuyuki
The Second Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
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MURAKAMI Keiji
The Second Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus
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