Kinetics of Pulmonary Gas Exchange During and While Recovering From Exercies in Patients After Anterior Myocardial Infarction

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• The effect of exercise intensity on gas exchange kinetics was investigated during exercise and recovery, as well as the relationship between the kinetics during exercise and recovery. Twenty-three patients with a history of anterior myocardial infarction performed low-intensity(38.7±8.3W)and high-intensity(68.8±15.0W)exercise for 6 min. The time constants of oxygen uptake(VO_2), carbon dioxide output(VCO_2)and minute ventilation (VE)were significantly prolonged during high intensity exercise compared with low-intensity exercise(61.2±8.6 vs 52.3±10.3s , p<0.005 for the time constant of VO_2). The time constant of VO_2 was similar during exercise and during recovery from exercise of high(61.2±8.6 vs 66.2±12.2 s)as well as low intensity(52.3±10.3 vs 55.0±10.1 s). However, the time constants of VCO_2 and heart rate were significantly shorter during recovery than during exercise. The time constants of VCO_2 and VE were significantly longer than that of VO_2 during both exercise and recovery. In the present study, it was found that(1)the gas exchange kinetics were influenced by the intensity of exercise;(2)the kinetics during recovery did not necessarily reflect the kinetics during exercise except for VO_2;and (3)the kinetics of VCO_2 and VE were delayed as compared with the VO_2 kinetics. These characteristics should be taken into account when using gas exchange kinetics to estimate cardiopulmonary responses to exercise in patients with left ventricular dysfuntion.

• 社団法人日本循環器学会の論文
• 1999-05-20

著者

• Hiroe Michiaki

  Department Of Clinical Pharmacology And Therapeutics Tohoku University

• MARUMO FUMIAKI

  Second Department of Internal Medicine, Tokyo Medical and Dental University

• Koike Akira

  The Cardiovascular Institute

• Koike Akira

  Department of Cardiology, The Cardiovascular Institute Hospital

• Koike Akira

  心臓血管研究所

• Hiroe Michiaki

  Department Of Medicine Tokyo Medical And Dental University

• Koike Akira

  Japanese Cardiac Rehabilitation Research Group (Ministry of Health, Labor, and Welfare 15A-2)

• Marumo Fumiaki

  Department Of Nephrology Tokyo Medical And Dental University

• Marumo Fumiaki

  The Second Department Of Medicine Tokyo Medical And Dental University

• Marumo Fumiaki

  Second Department Of Internal Medicine Faculty Of Medicine Tokyo Medical And Dental University

• Hiroe Michiaki

  Second Department of Internal Medicine, Tokyo Medical and Dental University

• Koyama Yoshiharu

  Second Department of Internal Medicine, Tokyo Medical and Dental University

• Kobayashi Kazuo

  Hokushin General Hospital

• Shimizu Noritaka

  Second Department of Internal Medicine

• Kobayashi Kazuo

  Second Department of Internal Medicine

• KOYAMA Yoshiharu

  Tokyo Kyosai Hospital

• Shimizu Noritaka

  Toride Kyoda General Hospital

• Marumo Fumiaki

  Second Department Of Medicine Tokyo Medical And Dental University

• Hirose Makoto

  The Department Of Nephrology And Cardiology International Medical Center Of Japan

• Hiroe Michiaki

  Second Department Of Internal Medicine Tokyo Medical And Dental University

• Koike Akira

  Japanese Cardiac Rehabilitation Research Group (ministry Of Health Labor And Welfare 15a-2)

• Koike Akira

  Department Of Critical Care Medicine Tokyo Medical And Dental University

• Marumo Fumiaki

  Institute Of Geriatrics Department Of Cardiology Department Of Radiology And Departement Of Patholog

• Marumo Fumiaki

  Institute Of Geriatrics Department Of Cardiology Department Of Radiology And Departement Of Patholog

• Hiroe Michiaki

  Second Department Of Internal Medicine

• Marumo Fumiaki

  Institute Of Geriatrics Department Of Cardiology Department Of Radiology And Departement Of Patholog

• Marumo Fumiaki

  Institute Of Geriatrics Department Of Cardiology Department Of Radiology And Departement Of Pathology Tokyo Women's Medical College The 2nd Department Of Medicine Tokyo Medical And Dental University

• Koike Akira

  Department Of Cardiology Cardiovascular Institute

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