Effects of combined changes in serum calcium and potassium on QT interva. A study by holter electrocardiographic monitoring during hemodialysis.:A Study by Holter Electrocardiographic Monitoring during Hemodialysis
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概要
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Holier electrocardiographic recordings were performed for 24 hours in 20 patients on chronic hemodialysis to evaluate the effect of changes in serum calcium and potassium during a 5-hour hemodialysis period on the QT interval. Hemodialysis caused an acute increase in serum calcium from a predialysis value of 9.6±1.3mg/dl to 11.5±.2 mg/dl and a decrease in serum potassium from 4.9±0.6mEq/L to 3.5±0.4mEq/L. The Q oTc interval shortened from a predialysis value of 0.240±0.023 sec to a minimum of 0.215±0.022 sec during the 5th hour of hemodialysis. This Q oTc interval shortening was correlated strongly with an increase in serum calcium and was statistically significant only in subjects showing an increase in serum calcium of more than 2mg/dl (p<0.05). The Q-eTc interval increased from a predialysis value of 0.392±0.030 sec to 0.414±0.024 sec during the 4th hour of hemodialysis. This Q-eTc interval prolongation was correlated with a decrease in serum potassium. It was concluded that increased serum calcium during hemodialysis caused shortening of the Q-oTc interval, that the degree of shortening was proportional to the magnitude of increase in serum calcium, and that changes in serum calcium and the Q oTc interval were concurrent. It was also concluded that hemodialysis resulted in prolongation of the Q eTc interval. This change was possibly caused by a decrease in the level of serum potassium during the procedure.
- International Heart Journal刊行会の論文
著者
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HASHIBA Kunitake
Third Department of Internal Medicine and Central iagnostic Laboratory, Nagasaki University School of Medicine
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AHMED Rafique
Third Department of Internal Medicine, Nagasaki University School of Medicine
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KIYA Fumihiro
Third Department of Internal Medicine, Nagasaki University School of Medicine
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TAKAGI Hiroyuki
Koseikai Hospital
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KITANO Koei
Third Department of Internal Medicine, Nagasaki University School of Medicine
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