A Clinicopathological Study on Cardiac Lesions in 64 Cases of Disseminated Intravascular Coagulation
スポンサーリンク
概要
- 論文の詳細を見る
Diagnosis of disseminated intravascular coagulation (DIC) was made in 64 cases (16.2%) among a total of 395 autopsy cases. There were 31 men and 33 women. Their ages ranged from 31 to 91 years (mean 76.3). Underlying diseases were mainly malignancy and sepsis.Fresh cardiac lesions were found in 40 cases (62.5%). Coronary thrombosis was found in 13 cases (20.3%) and myocardial necrosis in 24 cases (37.5%), with acute myocardial infarction in 9 and focal necrosis in 15. Nonbacterial thrombotic endocarditis was found in 17 cases (26.6%), mural thrombi in 11 (17.2%), and bleeding of the heart in 11 (17.2%). Platelet count, fibrinogen and euglobulin lysis time were not correlated with myocardial necrosis nor coronary thrombosis. Increase of fibrin degradation products correlated with the presence of coronary thrombosis with or without myocardial necrosis.DIG was found with a high incidence in the aged, and many of them were complicated with fresh cardiac lesions. Development of acute myocardial infarction depends on the small thrombi in the severe stenosis of the main coronary arteries or on the multiple microthrombi in the peripheral coronary branches.
- International Heart Journal刊行会の論文
著者
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MURAKAMI Mototaka
Department of Internal Medicine,Tokyo Metropolitan Geriatric Hospital
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Sugiura Masaya
Department Of Cardiology Tokyo Metropolitan Hiroo General Hospital
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Ohkawa Shin-ichiro
Department Of Cardiology Tokyo Metropolitan Geriatric Hospital
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HIRAOKA Keisuke
Department of Internal Medicine, Yoiku-in Hospital, Tokyo Municipal Home for the Aged
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Ueda Keiji
Department Of Cardiology Tokyo Metropolitan Geriatric Hospital
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MATSUDA Tamotsu
Department of Clinical Physiology, Tokyo Metropolitan Institute of Gerontology
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HIRAOKA Keisuke
Department of Internal Medicine and Department of Pathology, Tokyo Metropolitan Geriatric Hospital (Yoiku-in)
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MURAKAMI Mototaka
Department of Internal Medicine (II), School of Medicine, University of Kanazawa
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MURAKAMI Mototaka
Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital (Yoiku-in)
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SUGIURA Masaya
Department of Internal Medicine, Tokyo Metropolitan Geriatric Hospital (Yoiku-in)
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