Effects of Branched-Chain Amino Acid Supplementation on Plasma Concentrations of Free Amino Acids, Insulin, and Energy Substrates in Young Men
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概要
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The present study was conducted to examine alterations in the concentrations of plasma free amino acids, glucose, insulin, free fatty acids (FFAs), and urea nitrogen induced by branched-chain amino acid (BCAA) supplementation in young men. Overnight-fasted subjects ingested drinks containing 1 or 5 g of a BCAA mixture (weight ratio of 1 : 2.3 : 1.2 for isoleucine : leucine : valine), and blood was intermittently collected for 3 h after ingestion. Ingestion of the BCAA mixture resulted in significant increases in the plasma concentrations of individual BCAAs, corresponding to the amounts of amino acids ingested. On the other hand, plasma concentrations of methionine and aromatic amino acids tended to decrease in the trial with 5 g BCAAs, suggesting that BCAA ingestion affects the metabolism of these amino acids. The ingestion of BCAAs temporarily increased plasma insulin levels and affected plasma concentrations of FFAs, but had almost no effect on glucose or urea nitrogen.
著者
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Sato Juichi
Department of General Medicine, Nagoya University Hospital
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Bajotto Gustavo
Laboratory Of Nutritional Biochemistry Department Of Applied Molecular Biosciences Graduate School O
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SHIMOMURA Yoshiharu
Laboratory of Nutritional Biochemistry, Department of Applied Molecular Biosciences, Graduate School
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KOBAYASHI Hisamine
Ajinomoto Co. Inc.
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MAWATARI Kazunori
Ajinomoto Co. Inc.
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ZHANG Yi
Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sc
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KITAURA Yasuyuki
Laboratory of Molecular and Cellular Regulation, Department of Applied Molecular Biosciences, Gradua
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