Rheumatoid Arthritis following a Treatment with IFN-alpha/Ribavirin against HCV Infection
スポンサーリンク
概要
- 論文の詳細を見る
We report a 48-year-old man who developed rheumatoid arthritis (RA) after a successful treatment with peg-IFN-alpha plus ribavirin for chronic hepatitis C virus (HCV) infection. He had a history of smoking and a single copy of the HLA-DRB1 shared epitope (SE). In a retrospective analysis, he exhibited the anti-CCP antibodies before the start of IFN plus ribavirin treatment. However, the titers of anti-CCP antibodies and BAFF levels were elevated by the IFN plus ribavirin therapy. These observations suggest that IFN plus ribavirin therapy may work as a "trigger" for RA in genetically and environmentally predisposed individuals by affecting the cytokine network.
著者
-
YATSUHASHI HIROSHI
Department of Hepatology, National Hospital Organization Nagasaki Medical Center
-
Hashimoto Satoru
Department Of Anesthesiology And Intensive Care Kyoto Prefectural University Of Medicine
-
Migita Kiyoshi
Department Of General Internal Medicine And Rheumatology Nho National Nagasaki Medical Center
-
Izumi Yasumori
Department Of General Internal Medicine And Rheumatology Nho National Nagasaki Medical Center
-
Ishibashi Hiromi
Department Of Hepatology Nagasaki University Graduate School Of Biomedical Sciences
-
Miyashita Taiichiro
Department Of General Internal Medicine And Rheumatology Nho National Nagasaki Medical Center
-
Yatsuhashi Hiroshi
Department of Hepatology, NHO Nagasaki Medical Center, Japan
-
Migita Kiyoshi
Department of Rheumatology, NHO Nagasaki Medical Center, Japan
-
Komori Atsumasa
Department of Hepatology, NHO Nagasaki Medical Center, Japan
-
Yasunaga Yuki
Department of Hepatology, NHO Nagasaki Medical Center, Japan
-
Abiru Seigo
Department of Hepatology, NHO Nagasaki Medical Center, Japan
関連論文
- Association of subacute cutaneous lupus erythematosus in a rheumatoid arthritis patient with Sjogren's syndrome
- Two cases of hepatopulmonary syndrome with improved liver function following long-term oxygen therapy
- Fas Ligand Released by Activated Monocytes Causes Apoptosis of Lung Epithelial Cells in Human Acute Lung Injury Model in Vitro(Molecular and Cell Biology)
- Rheumatoid Arthritis following a Treatment with IFN-alpha/Ribavirin against HCV Infection
- Severe Legionella pneumophila pneumonia associated with the public bath on a cruise ship in Japan
- Five-day pain management regimen using patient-controlled analgesia facilitates early ambulation after cardiac surgery
- Histochemical Expression of Inducible Nitric Oxide Synthase and Inflammatory Cytokines in Alveolar Macrophages in Patients with ARDS
- EFFECT OF NICARDIPINE HYDROCHLORIDE ON CIRCULATING BLOOD VOLUME AND VASCULAR COMPLIANCE IN DOGS
- In rheumatoid arthritis patients treated with tocilizumab, the rate of clinical disease activity index (CDAI) remission at 24 weeks is superior in those with higher titers of IgM-rheumatoid factor at baseline
- Disease activity score 28 may overestimate the remission induction of rheumatoid arthritis patients treated with tocilizumab : comparison with the remission by the clinical disease activity index
- A case of lupus-associated pancreatitis with ruptured pseudoaneurysms
- Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients
- Successful treatment of severe asthma-associated plastic bronchitis with extracorporeal membrane oxygenation
- Leukocytapheresis (LCAP) for treating refractory adult-onset Still's disease (AOSD)
- High serum matrix metalloproteinase 3 is characteristic of patients with paraneoplastic remitting seronegative symmetrical synovitis with pitting edema syndrome
- Thyroid papillary carcinoma with solid sclerosing change in IgG4-related sclerosing disease
- Successful Treatment of HTLV-1-Related Overlap Syndrome Using Tacrolimus
- The need for an organized ECMO-based respiratory program in Japan
- Data mining reveals complex interactions of risk factors and clinical feature profiling associated with the staging of non-hepatitis B virus/non-hepatitis C virus-related hepatocellular carcinoma
- Serum amyloid A (SAA) induces pentraxin 3 (PTX3) production in rheumatoid synoviocytes
- Three Patients with Familial Mediterranean Fever: A Possible Underdiagnosed Entity in Japan
- Epstein-Barr virus and methotrexate-related CNS lymphoma in a patient with rheumatoid arthritis
- Coexistence of polymyositis and familial Mediterranean fever
- Challenging airway management : Opening remarks