Successful Remission of Evans Syndrome Associated with Graves Disease by Using Propylthiouracil Monotherapy
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概要
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A 46-year-old woman with Graves disease was admitted for anemia and thrombocytopenia. She had previously been treated with methimazole but she self-discontinued the treatment 6 months prior to admission. She was diagnosed with Evans syndrome associated with Graves disease and treated with propylthiouracil without corticosteroids, which normalized her thyroglobulin level. Surprisingly, while Evans syndrome is characterized by frequent relapses, this patient has been in remission of Evans syndrome for approximately 4 years. The remission of Evans syndrome associated with Graves disease in the absence of immunosuppressive therapy suggests that these 2 diseases have a common pathogenetic mechanism.
著者
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Toba Ken
Department of Hematology, Niigata University Graduate School of Medical and Dental Sciences
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Ushiki Takashi
Department of Clinical Pharmacokinetics, School of Pharmacy and Pharmaceutical Sciences, Hoshi Unive
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Takai Kazue
Department Of Hematology Niigata City General Hospital
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Morikawa Hiroshi
Department Of Applied Chemistry Faculty Of Engineering Kanagawa Institute Of Technology
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Aizawa Yoshifusa
Department Of Cardiology Keio University School Of Medicine
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Nikkuni Koji
Department of Hematology, Niigata City General Hospital, Japan
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Fuse Ichiro
Bioscience Medical Research Center, Niigata University Medical and Dental General Hospital, Japan
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Usami Akio
Usami Clinic, Japan
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Masuko Masayoshi
Department of Stem Cell Transplantation, Niigata University Medical and Dental General Hospital, Japan
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Terukina-Yoshida Jun
Department of Hematology, Niigata City General Hospital, Japan
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Momotsu-Nanba Ayako
Department of Hematology, Niigata City General Hospital, Japan
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Takai Kazue
Department of Hematology, Niigata City General Hospital, Japan
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