The Infectivity and Pathogenicity of a Group 2 Bovine Coronavirus in Pups
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概要
- 論文の詳細を見る
Canine respiratory coronavirus (CRCoV), which is more closely related to the bovine coronavirus (BCoV), has recently been detected in dogs. In this study, we examined whether BCoV was capable of infecting and exhibiting pathogenicity in dogs. Three 1-month-old pups were oronasally given field isolates of BCoV, and were kept together with 2 control animals. As a result, increases in BCoV-neutralizing antibody titers were confirmed in all pups in the challenged and control groups. Moreover, the virus gene was also detected in oral and rectal swabs by RT-PCR. These results indicate that BCoV infects dogs, and easily infects other dogs that are kept together. However, no clinical symptoms such as respiratory symptoms and diarrhea were observed.
- 公益社団法人 日本獣医学会の論文
著者
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Kaneshima Takashi
Department Of Veterinary Infectious Diseases School Of Veterinary Medicine And Animal Sciences Kitas
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Koyama Hiroyuki
Department Of Biotechnology Faculty Of Agriculture Gifu University
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HOHDATSU Tsutomu
Department of Veterinary Infectious Deseases, School of Veterinary Medicine and Animal Sciences, Kitasato University
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HOHDATSU Tsutomu
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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TSUNEMITSU Hiroshi
Viral Diseases Research Team, National Institute of Animal Health
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NOJIRI Yui
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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HAGINO Ryoko
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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HOSOYA Sakiko
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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MURATA Michiko
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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TAKANO Tomomi
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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TANABE Maki
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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KANESHIMA Takashi
Department of Veterinary Infectious Disease, School of Veterinary Medicine and Animal Science, Kitasato University
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TANABE Maki
Department of Analytic Human Pathology, Nippon Medical School
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