Effect of N-Acetyl-D-Glucosamine on Gene Expression in Vibrio parahaemolyticus
スポンサーリンク
概要
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We analyzed the effect of N-acetyl-D-glucosamine (GlcNAc) on gene expression in the marine bacterium Vibrio parahaemolyticus. The total number of genes whose expression was induced and repressed genes in the presence of GlcNAc was 81 and 55, respectively. The induced genes encoded a variety of products, including proteins related to energy metabolism (e.g. GlcNAc and chitin utilization), transport, central metabolism and chemotaxis, hypothetical proteins, mannose-sensitive hemagglutinin pilus (MSHA), and a PilA protein, whereas the repressed genes encoded mainly hypothetical proteins. GlcNAc appears to influence directly or indirectly a variety of cellular processes, including energy metabolism, chitin utilization, competence, biofilm formation and pathogenicity. GlcNAc, one of the most abundant aminosugars in the oceans, is used by V. parahaemolyticus as an energy source and affects the cellular functioning of this marine bacterium.
- 日本微生物生態学会・日本土壌微生物学会の論文
著者
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IIDA Tetsuya
Laboratory I Nano Process Technology Department, Corporate Research and Development, Laboratories Re
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Thompson Fabiano
Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro (UFRJ)
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Neto Antonio
Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro (UFRJ)
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Santos Eidy
Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro (UFRJ)
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Izutsu Kaori
Laboratory of Genomic Research on Pathogenic Bacteria, International Research Center for Infectious
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