Diphenylhydantoin-Induced Severe yet Reversible Anemia during Pregnancy
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概要
- 論文の詳細を見る
Diphenylhydantoin (DPH) therapy, often used in treating epileptic seizures, can cause anemia in some patients. A 26-year-old female suffered from convulsions due to encephalitis and was placed on DPH therapy. About two months after the initiation of DPH therapy, her hemoglobin level was 3.8 g/dL. Her anemia improved after the discontinuation of DPH, confirming that the anemia was caused by DPH. Pure red-cell aplasia (PRCA) combined with hemolytic anemia was indicated by results such as erythroid aplasia, an increased LDH level, and a decreased haptoglobin level. PRCA complicated by hemolytic anemia could be responsible for anemia associated with DPH.
- 社団法人 日本内科学会の論文
著者
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Tamaoka Akira
Department Of Neurology Institute Of Clinical Medicine University Of Tsukuba
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Okoshi Yasushi
Department Of Clinical And Experimental Hematology Doctoral Program In Advanced Biomedical Applicati
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Okoshi Yasushi
Department of Experimental and Hematology, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Sugaya Akinori
Department of Neurology, Institute of Clinical Medicine, University of Tsukuba
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Nakamagoe Kiyotaka
Department of Neurology, Institute of Clinical Medicine, University of Tsukuba
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Obata-Yasuoka Mana
Department of Obstetrics and Gynecology, Graduate School of Comprehensive Human Science, University of Tsukuba
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