Paradoxical Development of a Sarcoid-Like Reaction during Successful Chemotherapy for Seminoma
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概要
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Although the association between seminoma and sarcoidosis or a sarcoid-like reaction has been well recognized, a paradoxical case during chemotherapy for seminoma has not been reported. We report the first case of a sarcoid-like reaction that developed paradoxically during successful chemotherapy for recurrent seminoma. A 36-year-old Japanese man had recurrent seminoma in abdominal lymph nodes four years after left orchiectomy. Chemotherapy consisting of bleomycin, etoposide and cisplatin had reduced the abdominal mass, but mediastinal and bilateral hilar lymphadenopathy newly appeared. Surgical biopsy of the mediastinal lymph nodes and left nephrectomy and retroperitoneal lymphadenectomy revealed noncaseating granulomas only in mediastinal lymph nodes and confirmed complete remission of seminoma. Nine months later the thoracic lymphadenopathy had resolved spontaneously.
著者
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OKUMURA Kazuhiro
Department of urology, Faculty of Medicine, Kyoto University
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Okumura Kazuhiro
Department Of Urology Tenri Hospital
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Tanizawa Kiminobu
Department of Respiratory Medicine, Tenri Hospital
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Tanaka Eisaku
Department of Respiratory Medicine, Tenri Hospital
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Hashimoto Seishu
Department of Respiratory Medicine, Tenri Hospital
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Noma Satoshi
Department of Radiology, Tenri Hospital
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Kobashi Yoichiro
Department of Pathology, Tenri Hospital
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Shindo Toru
Department of Thoracic Surgery, Tenri Hospital
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Taguchi Yoshio
Department of Respiratory Medicine, Tenri Hospital
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Taguchi Yoshio
Department Of Neurosurgery The Jikei University School Of Medicine
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Kobashi Yoichiro
Department Of Pathology Tenri Hospital
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Noma Satoshi
Department Of Radiology Tenri Hospital
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Okumura Kazuhiro
Department Of Bacteriology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical Sciences
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TANAKA Eisaku
Department of Infectious Disease, Kyoto University
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Tanizawa Kiminobu
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
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