Synthesis of Some New Spiropyranoquinolines and Evaluation of Their Free Radical Scavenging Activity
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概要
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The preparation of some new spiro-substituted 4-hydroxypyranoquinolinones and their corresponding dihydropyrano cis-diols is described. The free radical scavenging activity of the compounds was determined by means of their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and the superoxide anions generated by the enzymic xanthine–xanthine oxidase system. The spiroadamatylpyranoquinolinone analogue proved to be the most efficient free radical scavenger.
著者
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ANDREADOU Ioanna
Department of Pharmaceutical Chemistry, School of Pharmacy, University of Athens
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Panteleon Vassiliki
Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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Kostakis Ioannis
Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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Marakos Panagiotis
Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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Pouli Nicole
Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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Marakos Panagiotis
Department Of Pharmacy Division Of Pharmaceutical Chemistry University Of Athens
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Andreadou Ioanna
Department Of Pharmaceutical Chemistry University Of Athens School Of Pharmacy
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Andreadou Ioanna
Department Of Pharmaceutical Chemistry School Of Pharmacy University Of Athens
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Andreadou Ioanna
Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens
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