Efficient Synthesis of p-Quinols Using Catalytic Hypervalent Iodine Oxidation of 4-Arylphenols with 4-Iodophenoxyacetic Acid and Oxone

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概要

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• Efficient synthesis of p-quinols (2) using catalytic hypervalent iodine oxidation of 4-arylphenols (1) with 4-iodophenoxyacetic acid (3) and Oxone® was developed. Reaction of 1 with a catalytic amount of 3 in the presence of Oxone® as a co-oxidant in tetrahydrofuran or 1,4-dioxane–water gave the corresponding 2 in excellent yields.

• 公益社団法人 日本薬学会の論文

著者

• Omoto Masanori

  Graduate School Of Medicine And Pharmaceutical Sciences University Of Toyama

• Yakura Takayuki

  Graduate School Of Medicine And Pharmaceutical Sciences Univ. Of Toyama

関連論文

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• Efficient Synthesis of p-Quinols Using Catalytic Hypervalent Iodine Oxidation of 4-Arylphenols with 4-Iodophenoxyacetic Acid and Oxone

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