Light Chain Deposition Disease Developing 15 Years Following the Diagnosis of Monoclonal Gammopathy of Undetermined Significance
スポンサーリンク
概要
- 論文の詳細を見る
A 64-year-old woman was admitted because of leg edema. Fifteen years previously she had been diagnosed with monoclonal gammopathy of undetermined significance (MGUS). Urinary immunoelectrophoresis demonstrated positivity for IgA kappa light chains. Bone marrow aspiration revealed a mild plasmacytosis. Her renal biopsy specimen revealed thickened basement membrane, mesangial cell proliferation and an increase in the mesangial matrix. Immunofluorescence studies showed the deposition of kappa light chains in the capillary wall and nodular lesions. These findings confirmed a diagnosis of light chain deposit disease (LCDD) with MGUS. The development of LCDD in patients with MGUS for fifteen years is very rare.
- 社団法人 日本内科学会の論文
著者
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HIGAKI Jitsuo
Department of Integrated Medicine and Informatics, Ehime University Medical School
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OKURA Takafumi
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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KURATA Mie
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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IRITA Jun
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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MIYOSHI Ken-ichi
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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Kurata Mie
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
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Irita Jun
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
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Irita Jun
愛媛大学 医学系研究科病態情報内科学
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Okura Takafumi
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
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Miyoshi Ken-ichi
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
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Nagao Tomoaki
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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Jotoku Masanori
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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Enomoto Daijiro
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine
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Nagao Tomoaki
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
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Jotoku Masanori
Department Of Cardiology Uwajima Social Insurance Hospital
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Enomoto Daijiro
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
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Higaki Jitsuo
Department of Cardiology, Pulmonology, Hypertension & Nephrology, Ehime University Graduate School of Medicine, Japan
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